波谱学杂志2017，Vol.34Issue(2)：191-199,9.DOI:10.11938/cjmr20170208
卡巴他赛结构确证的波谱学研究
Spectroscopic Studies and Structural Elucidation of Cabazitaxel
余大海 1康旺 1郝福 1李志刚1
作者信息
- 1. 神威药业集团有限公司,河北三河065201
- 折叠
摘要
Abstract
Infrared, ultraviolet, NMR (i.e.,1H NMR,13C NMR, DEPT-135, COSY, HSQC and HMBC), and mass spectroscopic data of cabazitaxel were collected and interpreted. Differential thermal analysis, X-ray power diffraction and elementary analysis were also used to characterize the compound. All1H and13C NMR signals were assigned. Possible fragmentation pathways were discussed based on the information provided by the mass spectra. The infrared spectrum was used to analyze the types of vibration of the functional groups in the compound. The structure of the compound was determined.关键词
卡巴他赛/核磁共振(NMR)/红外吸收光谱/质谱/结构确证Key words
cabazitaxel/NMR/infrared spectroscopy/mass spectroscopy/structural elucidation分类
数理科学引用本文复制引用
余大海,康旺,郝福,李志刚..卡巴他赛结构确证的波谱学研究[J].波谱学杂志,2017,34(2):191-199,9.
