重庆医学2017，Vol.46Issue(16)：2190-2192,3.DOI:10.3969/j.issn.1671-8348.2017.16.009
无法手术的中晚期胰腺癌HIFU治疗后的生存分析
Survival analysis of unresectable advanced pancreatic cancer after high intensity focused ultrasound therapy
摘要
Abstract
Objective To observe the 2-year survival situation of high intensity focused ultrasound(HIFU) treatment in unr esectable advanced pancreatic carcinoma.Methods Thirty-eight patients with unresectable pancreatic cancer received HIFU treatment.After treatment,the changes of laboratory tumor markers examination results,pain score,life quality score and survival situation were recorded.Results Among 35 patients with pain symptom before HIFU treatment,pain was relieved after HIFU treatment in 28 cases,the remission rate was 80.0％.The CA19-9 and CEA levels after HIFU therapy were obviously reduced compared with before treatment.The imaging examination showed the coagulation necrosis in HIFU-treated area.It was found the tumor volume was obviously shrunk during follow-up period.The median survival period was extended to (12.9 ± 6.6) months.Conclusion The HIFU treatment can effectively improve the life quality in the patients with unresectable pancreatic cancer and extends their survival period.关键词
高强度聚焦超声/中晚期胰腺癌/生存分析Key words
high intensity focused ultrasound/advanced pancreatic cancer/survival analysis分类
医药卫生引用本文复制引用
张喆,金成兵,周崑,冉立峰,杨炜..无法手术的中晚期胰腺癌HIFU治疗后的生存分析[J].重庆医学,2017,46(16):2190-2192,3.基金项目
国家重点基础研究发展计划(973计划)资助项目(2011GB707900). （973计划）
