摘要
Abstract
Objective To investigate the changes of arterial blood flow in pregnant women with severe preeclampsia(SPE) and fetuses and the effect of magnesium sulfate on it.Methods One hundred and seventy-four SPE pregnant women in our hospital from January 2013 to January 2015 were selected as the observation group and 174 normal pregnant women as the control group.The observation group was given the magnesium sulfate treatment for 2 d.The arterial blood flow changes of middle cerebral artery,uterine artery,uterine spiral artery,umbilical artery,fetal middle cerebral artery before and after treatment in the observation group were observed.And maternal blood pressure,dizziness symptoms,no load test(NST) changes were also observed.Results The RI,PI and S/D values of pregnant women and fetal middle cerebral artery before and after treatment had no statistical differences between the control group and observation group(P＞0.05).The RI,PI and S/D values of uterine artery and uterine spiral artery before treatment in the observation group were significantly higher than those in the control group(P＜0.05);the RI,PI and S/D values of uterine artery and uterine spiral artery after treatment in the observation group were significantly lower than those before treatment(P＜0.05).The umbilical artery RI,PI and S/D values before treatment in the observation group were higher than those in the control group(P＜0.05);the PI and S/D values after treatment were lower than those before treatment,but difference was statistically significant(P＞0.05).The systolic pressure,diastolic pressure and mean arterial blood pressure after treatment in the observation group were decreased compared with treatment,and the proportion of dizziness was decreased compared with before treatment,but the difference was not statistically significant(P＞0.05),while the incidence rate of NST no response was significantly lower than that before treatment(P＜0.05).Conclusion The magnesium sulfate therapy can significantly improve the blood flow situation of uterine artery and uterine spiral artery in the patients with SPE and can improve fetal intrauterine reserve.关键词
重度子痫前期/硫酸镁/子宫动脉/大脑中动脉/脐动脉Key words
severe pre-eclampsia/magnesium sulfate/uterine artery/middle cerebral artery/umbilical arteries分类
医药卫生
