摘要
Abstract
Objective:To systematically evaluate the most suitable timing of laparoscopic cholecystectomy for acute cholecystitis.Methods:The Chinese data of randomized controlled trials to compare early and delayed laparoscopic cholecystectomy for acute cholecystitis were searched in WANFANG,CNKI and Chinese Technology Periodical Database from establishment to Aug.2016.Data were selected,extracted and evaluated by two independent researchers according to inclusion and exclusion criteria.Meta-analyses were conducted using the RevMan 5.3 software.Results:Fifteen controlled clinical trials (n=2 325) were included.After meta-analysis,the data collected in this study suggested that compared with delayed laparoscopic cholecystectomy,early laparoscopic cholecystectomy was associated with a lower rate of conversion to laparotomy [OR=0.55,95% CI(0.37,0.83),P=0.004],a lower rate of complications [OR=0.64,95% CI(0.45,0.91),P=0.01] and shorter operation time [MD=-3.69,95% CI(-5.46,-1.92),P<0.0001],the differences were statistically significant.Conclusions:Compared with delayed laparoscopic cholecystectomy,early laparoscopic cholecystectomy within 72 h can reduce the rate of conversion to laparotomy,the rate of complications and operation time,and may be the most suitable timing of laparoscopic cholecystectomy for acute cholecystitis.关键词
胆囊炎,急性/胆囊切除术,腹腔镜/早期/延期Key words
Cholecystitis/acute/Cholecystectomy/laparoscopic/Early/Delayed分类
医药卫生
