口腔疾病防治2017，Vol.25Issue(6)：389-393,5.DOI:10.12016/j.issn.2096-1456.2017.06.010
正畸治疗对牙周病患者牙槽骨密度及表皮生长因子表达的影响
Effect of orthodontic treatment on alveolar bone density and epidermal growth factor expression in patients with periodontal disease
摘要
Abstract
Objective To study the effect of orthodontic treatment on alveolar bone density and epidermal growth factor (EGF) expression in patients with periodontal disease. Methods 50 patients with periodontal disease admitted into our hospital from January 2015 to January 2016 were selected as research object. Before treatment, patients were given dental health instruction. Under the conditions of patients agreeing and cooperating, patients received orthodontic treatment. The changes of alveolar bone density, EGF in blood, saliva, gingival crevicular fluid (GCF), indexes of peri-odontal inflammation (gingival index, papilla Bleeding index, probing depth) of patients before and after treatment for one month were compared. Results Before treatment, the mandibular alveolar bone density was significantly higher than maxillary alveolar bone density (P < 0.05); After treatment, the maxillary and mandibular alveolar bone density were significantly lower than before treatment, and maxillary bone density was significantly lower than mandibular bone density (P<0.05);After one-month treatment, the concentration of EGF expression in blood, saliva compared with be-fore treatment, there was no statistical significance (P>0.05);After one-month treatment, the concentration of EGF ex-pression in GCF was significantly higher than before treatment (P<0.05);Before and after treatment for one month, the concentration of EGF expression in GCF was significantly higher than blood, saliva (P<0.05);After treatment, the GI, PBI, PD levels were significantly lower than before treatment (P < 0.05); After treatment, flow of saliva and GCF were significantly higher than before treatment (P<0.05). Conclusion Orthodontic treatment has certain influence on EGF expression in GCF, but has no obvious influence on EGF expression in blood and saliva; The increase of EGF expres-sion derives from periodontal tissue cells and has close association with periodontal remodeling, periodontal tissue cells can promote self-remodeling through autogenous regulation and local humoral regulation.关键词
正畸治疗/牙周病/牙槽骨密度/表皮生长因子表达/炎症指标Key words
Orthodontic treatment/Periodontal disease/Alveolar bone density/Epidermal growth factor ex-pression/Inflammation index分类
医药卫生引用本文复制引用
黄丹丹..正畸治疗对牙周病患者牙槽骨密度及表皮生长因子表达的影响[J].口腔疾病防治,2017,25(6):389-393,5.基金项目
佛山市自筹经费类科技计划项目(2016AB003703) （2016AB003703）
