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丙戊酸钠与托吡酯治疗初诊癫痫患者效果对比

韩敬民

国际医药卫生导报2017,Vol.23Issue(12):1918-1920,3.
国际医药卫生导报2017,Vol.23Issue(12):1918-1920,3.DOI:10.3760/cma.j.issn.1007-1245.2017.12.033

丙戊酸钠与托吡酯治疗初诊癫痫患者效果对比

The comparison of the effect of sodium valproate and topiramate in the treatment of newly diagnosed epilepsy

韩敬民1

作者信息

  • 1. 457300 河南省清丰县人民医院神经内科
  • 折叠

摘要

Abstract

Objective To explore the effect of sodium valproate and topiramate in the treatment of patients with newly diagnosed epilepsy.Methods A total of 90 patients with newly diagnosed epilepsy were selected from January 2014 to December 2015.The patients were divided into group A and group B by random number method.Group A was treated with sodium valproate,while group B was treated with topiramate.Observed clinical efficacy and adverse drug reactions of the two groups.Results The total effective rate was 95.56% in group B,higher than that in group A (P<0.05).The incidence of adverse drug reactions in group B was 4.44%,and that in group A was 20.00%,with statistically significant difference (P<0.05).Conclusion Sodium valproate and topiramate have good effect in the treatment of patients with newly diagnosed epilepsy,but topiramate has better effect and higher safety.

关键词

丙戊酸钠/托吡酯/癫痫

Key words

Sodium valproate/Topiramate/Epilepsy

引用本文复制引用

韩敬民..丙戊酸钠与托吡酯治疗初诊癫痫患者效果对比[J].国际医药卫生导报,2017,23(12):1918-1920,3.

国际医药卫生导报

1007-1245

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