神经损伤与功能重建2017，Vol.12Issue(3)：225-227,3.DOI:10.16780/j.cnki.sjssgncj.2017.03.012
复发与首发精神分裂症患者认知功能损害的比较研究
A Comparative Study of Cognitive Impairments in Recurrent and First-episode Schizophrenia
罗晓玉 1王惠玲 1冒海赢 1王怡君 1李培福1
作者信息
- 1. 武汉大学人民医院精神卫生中心 武汉430060
- 折叠
摘要
Abstract
Objective:To acquire the differences in cognitive function between recurrent schizophrenia and first episode schizophrenia.Methods:Twenty-three cases of first-episode schizophrenia,25 cases of recurrent schizophrenia and 25 cases of healthy controls were recruited.Brief assessment of cognition in schizophrenia (BACS) was used to assess the cognitive function of cases in three groups.Psychiatric symptoms and severity were evaluated using positive and negative syndrome scale (PANSS).Results:There was no difference in psychiatric symptoms between first-episode schizophrenia and recurrent schizophrenia (P＞0.05).The results of cognitive test in first-episode schizophrenia and recurrent schizophrenia patients were both significant lower than that in healthy controls (P＜0.05).The performance of recurrent schizophrenia in category instances test and tower of London test were much worse than that in first-episode schizophrenia (P=0.029,P=0.035).No differences existed in list learning test,digit sequencing task,token motor task and symbol coding (P＞0.05).Conclusion:Our study not only indicated that cognitive impairment has occurred in the early stage of schizophrenia,but also proved that the cognitive function in recurrent schizophrenia was worse than that in first-episode schizophrenia.关键词
首发精神分裂症/复发精神分裂症/认知功能Key words
first-episode schizophrenia/recurrent schizophrenia/cognitive function分类
医药卫生引用本文复制引用
罗晓玉,王惠玲,冒海赢,王怡君,李培福..复发与首发精神分裂症患者认知功能损害的比较研究[J].神经损伤与功能重建,2017,12(3):225-227,3.
