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Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice

Eric E Beier Tzong-Jen Sheu Emily A Resseguie Masahiko Takahata Hani A Awad Deborah A Cory-Slechta J Edward Puzas

骨研究（英文版）2017，Vol.5Issue(2)：95-108,14.

骨研究（英文版）2017，Vol.5Issue(2)：95-108,14.DOI:10.1038/boneres.2017.13

Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice

Eric E Beier ¹Tzong-Jen Sheu ²Emily A Resseguie ³Masahiko Takahata ¹Hani A Awad ³Deborah A Cory-Slechta ³J Edward Puzas¹

作者信息

1. Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY, USA
2. Department of Environmental and Occupational Medicine, Rutgers University, Piscataway, NJ, USA
3. Center for Musculoskeletal Research, University of Rochester, School of Medicine and Dentistry, Rochester, NY, USA
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摘要

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Eric E Beier,Tzong-Jen Sheu,Emily A Resseguie,Masahiko Takahata,Hani A Awad,Deborah A Cory-Slechta,J Edward Puzas..Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice[J].骨研究（英文版）,2017,5(2):95-108,14.

基金项目

We thank R Tierney and S Mack for assistance with histology, R Gelein forbone Pb measurements, and M Thullen for microCT imaging and analysis.Biomechanical testing was performed in the Biomechanics and Multimodal Tissue Imaging Core laboratory, established by grant P30AR061307 from the National Institutes of Health (NIH). This work was supported by Public Health Service grants NIH T32 ES07026 and R01 ES012712, T32 AR053459,P01 ES011854, and P30 ES001247. （NIH）

骨研究（英文版）

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ISSN：2095-4700

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