环境工程学报2017，Vol.11Issue(6)：3341-3351,11.DOI:10.12030/j.cjee.201704158
环境介质中手性药物对映体分离分析及环境行为研究进展
Research progress on separation, analysis and environmental behavior of chiral pharmaceutical enantiomers in environmental matrix
摘要
Abstract
This paper reviewed the research progress on separation,analytical methods of chiral pharmaceuticals in the environmental samples and their environmental behaviors in aquatic environment.The main separation methods of enantiomers were compared.The types,characteristics,separation principle and influence factors of chiral stationary phase for the separation of enantiomers was described in detail,accordingly,development trend on enantiomers separation was proposed.Additionally,the degradation and transformation of pharmaceutical enantiomers in sewage treatment processes and natural water,as well as application of enantiomeric selectivity for chiral pharmaceuticals in the pollutant source apportionment were reviewed and discussed.关键词
环境介质/药物对映体/分离检测方法/环境行为Key words
environmental matrix/drug enantiomers/separation and detection method/environmental behavior分类
资源环境引用本文复制引用
刘瑞霞,李佳熹,刘晓玲..环境介质中手性药物对映体分离分析及环境行为研究进展[J].环境工程学报,2017,11(6):3341-3351,11.基金项目
国家自然科学基金资助项目(21277133) （21277133）
