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中药复方联合西药改善2型糖尿病胰岛素抵抗的Meta分析

向芬 郑承红

湖南中医药大学学报2017,Vol.37Issue(7):757-761,5.
湖南中医药大学学报2017,Vol.37Issue(7):757-761,5.DOI:10.3969/j.issn.1674-070X.2017.07.016

中药复方联合西药改善2型糖尿病胰岛素抵抗的Meta分析

Effects of Compound Traditional Chinese Medicine Combined with Western Medicine on Insulin Resistance in Type 2 Diabetes Mellitus:A Meta-Analysis

向芬 1郑承红2

作者信息

  • 1. 湖北中医药大学,湖北 武汉 430061
  • 2. 武汉市中医医院,湖北 武汉 430010
  • 折叠

摘要

Abstract

Objective By using the Meta-analysis, the compound traditional Chinese medicine (TCM) combined with Western medicine were applied to improve insulin resistance of type 2 diabetes mellitus (T2DM), and evaluate its clinical effi-cacy. Methods To retrieve fully the randomized clinical trial that the compound TCM combined with Western medicine were applied to improve insulin resistance of T2DM, and according to the literature selection criteria to filtrate them. Meta-analysis is applied to compare the compound of TCM combined with Western medicine to the western medicine, such as mefformin and so on. Results A total of 20 papers were included, the compound TCM combined with Western medicine in improving fasting blood glucose (FPG), glycosylated hemoglobin (HbA1C), insulin resistance index (HOME-IR) and insulin sensitive index (ISI) in patients with T2DM were better than only using Western medicine (P<0.05). Conclusion The curative effect of the compound TCM combined with Western medicine are better than that of Western medicine control group in improving insulin resistance of T2DM. However, the quality of selected papers are low, and the sample is small, which could affect the authen-ticity of the study results. We should research large sample of randomized clinical trials.

关键词

胰岛素抵抗/中药复方/Meta分析/随机对照试验

Key words

insulin resistance/compound TCM/Meta-analysis/randomized clinical trial

分类

医药卫生

引用本文复制引用

向芬,郑承红..中药复方联合西药改善2型糖尿病胰岛素抵抗的Meta分析[J].湖南中医药大学学报,2017,37(7):757-761,5.

湖南中医药大学学报

OACSTPCD

1674-070X

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