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云南红河哈尼族ABO、Rh血型分布规律及基因频率调查

丁权 王闳 余勤 张瞻

实用临床医药杂志2017,Vol.21Issue(11):62-64,3.
实用临床医药杂志2017,Vol.21Issue(11):62-64,3.DOI:10.7619/jcmp.201711019

云南红河哈尼族ABO、Rh血型分布规律及基因频率调查

Investigation on ABO and Rh blood group distribution and gene frequency of Honghe Hani nationality in Yunnan

丁权 1王闳 2余勤 3张瞻3

作者信息

  • 1. 云南省红河州中心血站,检验科, 云南 蒙自, 661100
  • 2. 云南省红河州中心血站,质控科, 云南 蒙自, 661100
  • 3. 云南省红河州中心血站,信息科, 云南 蒙自, 661100
  • 折叠

摘要

Abstract

Objective To explore the distribution of ABO and Rh blood group and the gene frequency of the voluntary blood donors in Honghe Hani autonomous prefecture of Yunnan province.Methods The blood group identification of 6 817 cases of voluntary blood donators in Honghe Hani nationality in Yunnan was carried out by the positive and negative ABO and Rh (D) screening and identification procedures.Results In Yunnan Honghe Hani people,type A,type B,type O and type AB accounted for 25.08%,27.92%,39.81% and 7.19% respectively,the expected value of the ratio was 25.19%,28.08%,40.02% and 6.73% respectively,the gene frequency of P was 0.1749,Q was 0.1925,r=0.6326,and there was no significant difference between the observation value and the expected value (P>0.05).Distribution was correlated with the Hardy-Weinberg equilibrium,and the distribution of ABO type was type O >type B >type A >type AB.In 6 817 Yunnan Honghe Hani people,RhD (-) were detected in 23 cases,accounted for 0.37%,including CCdee was 21.74%,Ccdee was 47.83%,ccdee was 30.43%,the expected value of the ratio was 20.87%,49.57% and 29.57%,the frequency of Cde gene was 0.4566,CDE was 0.5434,and there was no significant difference betweeen the observed and expected value (P>0.05).Distribution was correlated with the Hardy-Weinberg equilibrium.Conclusion The study on the distribution of ABO and Rh blood group and the gene frequency of the non remunerated blood donors of Hani nationality have important guiding significance for the establishment of blood collection and blood supply plan and the safety of blood.

关键词

哈尼族/ABO血型/Rh血型/基因频率

Key words

Hani nationality/ABO blood group/Rh blood group/gene frequency

分类

医药卫生

引用本文复制引用

丁权,王闳,余勤,张瞻..云南红河哈尼族ABO、Rh血型分布规律及基因频率调查[J].实用临床医药杂志,2017,21(11):62-64,3.

基金项目

云南省教育厅理工类重点项目(2014Z038) (2014Z038)

实用临床医药杂志

1672-2353

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