实用临床医药杂志2017,Vol.21Issue(11):108-110,119,4.DOI:10.7619/jcmp.201711032
洗胃及微量喂养对重症新生儿缺氧缺血性脑病胃肠功能紊乱的影响分析
Effect of lavage and micro-quantity feeding on severe gastrointestinal dysfunction in patients with severe hypoxic-ischemic encephalopathy
刘萍 1梅红1
作者信息
- 1. 华中科技大学同济医学院附属武汉市儿童医院 消化内科, 湖北 武汉, 430016
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摘要
Abstract
Objective To analyze the impact of gastric lavage and micro-quantity feeding on severe gastrointestinal dysfunction in patients with severe hypoxic-ischemic encephalopathy(HIE).Methods A total of 88 children with severe HIE in our department from July 2012 to June 2014 were randomly divided into experimental and control groups.The control group received routine feeding and comprehensive care,while the experimental group was given 1% sodium bicarbonate lavage,and micro-quantity feeding after fasting for 6 h.The improved clinical status,growth and development indicators,serum gastrin levels and the incidence of gastrointestinal disorders were compared in two groups.Results The body mass declined after birth,the time returning to birth weight,time to full enteral feeding and peak serum total bilirubin level in the experimental group were significantly lower than in the control group,body mass growth rate was significantly higher(P<0.05).Weight gain and head circumference growth at 7 and 14 days in the experimental group were significantly higher(P<0.05).Serum gastrin levels in experimental group on the first day,the third day and 7 days were significantly higher(P<0.05).Gastrointestinal dysfunction in experimental group was significantly lower than the control group(P<0.05).Conclusion For children with severe HIE,timely lavage and micro-quantity feeding can improve their nutritional status,promote early neonatal development and avoid the occurrence of gastrointestinal disorders.关键词
洗胃/微量喂养/重症新生儿缺氧缺血性脑病Key words
gastric lavage/micro-quantity feeding/severe hypoxic-ischemic encephalopathy分类
医药卫生引用本文复制引用
刘萍,梅红..洗胃及微量喂养对重症新生儿缺氧缺血性脑病胃肠功能紊乱的影响分析[J].实用临床医药杂志,2017,21(11):108-110,119,4.