临床口腔医学杂志2017，Vol.33Issue(6)：323-325,3.DOI:10.3969/j.issn.1003-1634.2017.06.002
掺锶透钙磷石涂层对去势大鼠种植支抗骨整合影响
Effect of strontium-substituted brushite coating on osseointegration of implant anchorage in osteoporotic rats
摘要
Abstract
Objective:To observe the effect of different concentrations of strontium-substituted brushite coating on the osseointegration of coating implant anchorages in osteoporotic rats.Methods:Totally 40 female SD rats were selected as the osteoporosis model and divided into 4 groups,eight rats in each group that were implanted different concentrations anchorages coated with strontium-brushite.And 8 normal rats were set up in the blank control group,implant anchorages with coated nothing.After 2,8 weeks implant loading,the rate of bone implant contact were calculated.Results:The mobility degree of the implant anchorages coated with strontium-brushite coating were zero.The bone implant contact rate of blank control group had significant difference with other groups after 2 weeks implants loading.After 8 weeks implants loading,the bone implant contact rate of 10% group had significant difference with other groups.Conclusion:The surface modification method of titanium alloy with strontium-brushite coating could effectively enhanced the effect of osseointegration and the stability of the implant anchorage.And the effect of 10% strontium-brushite coating was the best.关键词
种植体支抗/锶/透钙磷石/涂层/骨质疏松Key words
Implant anchorage/Strontium/Brushite/Coating/Osteoporosis分类
医药卫生引用本文复制引用
李淑静,周秋娟,李昕畅,闫玉婷,梁永强..掺锶透钙磷石涂层对去势大鼠种植支抗骨整合影响[J].临床口腔医学杂志,2017,33(6):323-325,3.基金项目
国家自然科学基金(81270965) （81270965）
河北省教育厅重点项目(ZD2015016) （ZD2015016）
