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铁皮石斛多糖的提取工艺及其治疗原发性干燥综合征疗效观察

肖胤 肖林 杨军 梁新华

临床口腔医学杂志2017,Vol.33Issue(6):363-365,3.
临床口腔医学杂志2017,Vol.33Issue(6):363-365,3.DOI:10.3969/j.issn.1003-1634.2017.06.015

铁皮石斛多糖的提取工艺及其治疗原发性干燥综合征疗效观察

Optimal extraction procedure of polysaccharides from tin caulis dendrobii and therapeutic effects of polysaccharides on patients with primary Sjgren's syndrome

肖胤 1肖林 1杨军 2梁新华3

作者信息

  • 1. 重庆市涪陵中心医院口腔颌面外科 重庆 408099
  • 2. 第三军医大学西南医院口腔颌面外科 重庆 400038
  • 3. 四川大学华西口腔医学院口腔颌面外科 成都 610041
  • 折叠

摘要

Abstract

Objective:To establish optimal extraction procedure of polysaccharides from tin caulis dendrobii and observe its curative effects on patients with primary Sjgren's syndrome.Methods:Orthogonal design was adopted,and time and times of boiling,solid-fluid ratio were selected as variable factors.The effects of patients with primary Sjgren's syndrome were observed by measuring the total curative effect,saliva flow and routine blood.Results:The most favorable extraction conditions were as follows,boiling 8 times and 0.5 hours each time with solid-fluid ratio of 1:20.Compared with before treatment,the static flow was increased in the two groups after treatment,and the polysaccharides groups increased more than the hydroxychloroquine sulfate group.The treatment efficiency of the polysaccharides group was 80%,and the efficiency of the hydroxychloroquine sulfate group was 73.33%.Conclusion:Polysaccharides from tin caulis dendrobii could improve the symptoms of patients with primary Sjgren's syndrome.

关键词

铁皮石斛/多糖分离/原发性干燥综合征/疗效/唾液流量

Key words

Tin caulis dendrobii/Polysaccharides extraction/Primary Sjgren's syndrome/Curative effect/Salivary flow

分类

医药卫生

引用本文复制引用

肖胤,肖林,杨军,梁新华..铁皮石斛多糖的提取工艺及其治疗原发性干燥综合征疗效观察[J].临床口腔医学杂志,2017,33(6):363-365,3.

基金项目

重庆市卫生局医学科研计划项目(2013-2-187) (2013-2-187)

临床口腔医学杂志

OACSTPCD

1003-1634

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