临床眼科杂志2017，Vol.25Issue(3)：219-222,4.DOI:10.3969/j.issn.1006-8422.2017.03.008
内界膜剥除联合或不联合玻璃体腔注射康柏西普治疗顽固性糖尿病黄斑水肿的疗效对比观察
Effects of internal limiting membrane peeling with or without intravitreal Conbercept in the treatment of refractory diabetic macular edema
郭婧 1陈松 2何广辉 2王健 2武斌 2李翠萍 1王萍 1李君慧1
作者信息
- 1. 300020 天津医科大学眼科临床学院
- 2. 天津市眼科医院 天津市眼科学与视觉科学重点实验室
- 折叠
摘要
Abstract
Objective To compare the effect of internal limiting membrane peeling with or without Intravitreal Conbercept in the treatment refractory diabetic macular edema (DME).Methods Thirty-six patients (36 eyes) with refractory macular edema secondary to diabetic retinopathy (DR) were enrolled.This cases were divided into a intravitreal Conbercept combined with internal limiting membrane peeling group of 16 eyes (combined group) and simple limiting membrane peeling group of 20 eyes (control group).Results Outcomes were significantly better in combined group as demonstrated by reduced retinal thickness and improved visual acuity.The CMT were 343.13±74.50μm、300.50±60.82 μm、267.88±56.30 μm at 1,3 and 6 months.in combined group, the CMT and logMAR BCVA were significantly better than preoperative situation (P<0.05).In control group, the improvement in BCVA was not not significantly at 1 month (P=0.097).The CMT decreased gradually at 1,3 and 6 months, they were 406.10±94.84 μm、327.65±88.91 μm、275.30±61.09 μm.The postoperative mean logMAR BCVA and CMT in combined group at 1 month were both better than that in control group (P<0.05).Conclusion Intravitreal Conbercept combined with internal limiting membrane peeling can facilitate the resolve of refractory diabetic macular edema.关键词
康柏西普/糖尿病黄斑水肿/玻璃体切除术/内界膜Key words
Conbercept/Diabetic macular edema/Vitrectomy/Internal limiting membrane引用本文复制引用
郭婧,陈松,何广辉,王健,武斌,李翠萍,王萍,李君慧..内界膜剥除联合或不联合玻璃体腔注射康柏西普治疗顽固性糖尿病黄斑水肿的疗效对比观察[J].临床眼科杂志,2017,25(3):219-222,4.
