中国临床保健杂志2017,Vol.20Issue(4):393-396,4.DOI:10.3969/J.issn.1672-6790.2017.04.017
门冬氨酸钾镁联合胺碘酮对慢性心力衰竭并室性心律失常患者心功能的影响
Effects of potassium magnesium aspartate combined amiodarone on cardiac function of chronic heart failure with ventricular arrhythmia patients
摘要
Abstract
Objective To investigate the effect of potassium magnesium aspartate combined amiodarone on cardiac functionof chronic heart failure with ventricular arrhythmia patients.Methods 232 cases of chronic heart failure with ventricular arrhythmia patients were randomly divided into observation group and control group,each group 116 cases.Patients in control group were given amiodarone,and patients in observation group were given potassium magnesium aspartate based on amiodarone.Before and after treatment,the blood pressure,heart rate,PR and QT interval,left ventricular end diastolic diameter (LVD),left ventricular ejection fraction (LVEF),left ventricular posterior wall thickness (LVWP) of two groups were detected,and the efficacy and adverse reaction were accounted.Results After treatment,heart rate of two groups were significantly reduced,PR and QT levels interval were significantly increased (P<0.05),and heart rate reduce of observation group was significantly better than that of control group,P-R and Q-T interval increase of observation group were significantly better than those of control group (P<0.05).After treatment,the LVD,LVEF and LVWP of two groups were significantly improved(P<0.05),and the LVD,LVEF and LVWP improvement of observation group were significantly better than those of control group(P<0.05).The efficiency of observation group was 83.6%,which was significantly higher than that of control group(72.4%),P<0.05.Conclusion Potassium magnesium aspartate combined amiodarone could effectively relieve cardiac systolic and diastolic function of chronic heart failure with ventricular arrhythmia,slow down the heart rate and restore normal ejection,with satisfactory treatment.关键词
心力衰竭/心律失常/心性/天冬氨酸钾镁/胺碘酮/治疗结果Key words
Heart failure/Arrhythmias/cardiac/Potassium magnesium aspartate/Amiodarone/Treatment outcome分类
医药卫生引用本文复制引用
牛美芝,解静,刘宁,杨辉,黄卫..门冬氨酸钾镁联合胺碘酮对慢性心力衰竭并室性心律失常患者心功能的影响[J].中国临床保健杂志,2017,20(4):393-396,4.基金项目
山东省科技发展计划项目(2014GSF118187) (2014GSF118187)