山东农业大学学报(自然科学版)2017,Vol.48Issue(3):351-354,4.DOI:10.3969/j.issn.1000-2324.2017.03.006
胃肠炎肉鸡肠黏膜及血清抗氧化因子和5-羟色胺变化规律研究
Study on the Changes of Antioxidant Factors and 5- Serotonin in Intestinal Mucosa and Serum of Gastroenteritis Broilers
摘要
Abstract
This paper aims to elucidate the change of antioxidant indexes SOD, GSH-Px, T-AOC, MAD and inflammatory factor 5-HT in digestive tract mucosa and serum of broiler chickens with digestive tract diseases. The natural cases of broiler chickens with gastroenteritis were selected as research object. Duodenum, jejunum, ileum and the contents of SOD, GSH-Px, T-AOC, MAD and 5-HT in serum were determined by enzyme-linked immune sorbent assay (ELISA).The results showed the levels of SOD, GSH-Px and T-AOC in the digestive tract and serum of broilers were significantly lower than those in healthy controls, the content of MAD was higher than that of healthy controls. Most index difference reached a significant level (P<0.05),the antioxidant function of the duodenum was lowest. The content of serum 5-HT in gastroenteritis broilers was significantly higher than that in healthy broilers (P<0.05). The content of 5-HT in jejunum and ileum of group A, duodenum and jejunum of group B,C, was significantly higher than that in healthy controls. The content of 5-HT in serum of gastroenteritis broiler and intestinal mucosa increased evidently, the antioxidant function decreased obviously and the active oxygen metabolites increased significantly.关键词
肉鸡/消化道疾病/抗氧化因子/活性氧代谢产物/5-羟色胺Key words
Broiler chickens/digestive tract/antioxidant/reactive oxygen metabolites/5-HT分类
农业科技引用本文复制引用
褚秀玲,王进圣,董月斌,苏建青,刘思当..胃肠炎肉鸡肠黏膜及血清抗氧化因子和5-羟色胺变化规律研究[J].山东农业大学学报(自然科学版),2017,48(3):351-354,4.基金项目
山东凤祥股份有限公司博士后基金资助(130101) (130101)