生物医学工程研究2017，Vol.36Issue(2)：187-190,4.DOI:10.19529/j.cnki.1672-6278.2017.02.19
颌骨组织工程血管化的研究进展
Research Progress on Vascularization of Jaw Bone Tissue Engineering
摘要
Abstract
With the development of tissue engineering technology, repairing jaw defects using tissue-engineered bone has become a hot topic.However, vascularization still remains an unsolved problem of this field, especially for repairing large volume jaw defects in clinical application.As the three essential elements of tissue engineering, Scaffold, cells and growth factors, play key roles in the vascularization of tissue-engineered constructs.Consequently, various in vitro and in vivo vascularization-promoting methods, such as optimization of scaffold composition and structure, loading of angiogenic cells and angiogenic factors, as well as the use of various surgical methods were recently extensively investigated.Therefore, the present paper aims to make a summary.关键词
血管化/颌骨/骨组织工程/支架材料/种子细胞/生长因子/外科手段Key words
Vascularization/Jaw/Bone tissue engineering/Scaffold/Seed cell/Growth factor/Surgical method分类
医药卫生引用本文复制引用
杨晓彬,周苗..颌骨组织工程血管化的研究进展[J].生物医学工程研究,2017,36(2):187-190,4.基金项目
国家自然科学基金资助项目(81671029) （81671029）
国际口腔种植协会基金资助项目(881-2012) （881-2012）
广东省科技计划项目(2013B021800314,2015B090920002). （2013B021800314,2015B090920002）
