生物骨科材料与临床研究2017，Vol.14Issue(3)：62-66,69,6.DOI:10.3969/j.issn.1672-5972.2017.03.017
二价阳离子掺杂羟基磷灰石的基础研究进展
Recent developments of experimental studies in divalent cations doped hydroxyapatite
摘要
Abstract
Doping ions into hydroxyapatite can synthesize an inorganic composite whose physicochemical and biological properties can be more excellent.This paper summarizes progress of three kinds of divalent cations doped hydroxyapatite on basic properties,in vitro and in vivo biological properties.The biocompatibility,biodegradability and osteoconductivity ofhydroxyapatite were enhanced by doping zinc,magnesium and strontium in vitro.In addition,doping zinc ions increases the performances of hydroxyapatite's anti-inflammatory and antibacterial.Doping strontium ions increases the performances ofhydroxyapatite's mechanical.Zinc,magnesium and strontium,these divalent cations doped hydroxyapatite in vivo experiments showed good bone repair capacity.关键词
羟基磷灰石/锌/镁/锶Key words
Hydroxyapatite/Zinc/Magnesium/Strontium分类
医药卫生引用本文复制引用
叶利远,王会丹,孟增东..二价阳离子掺杂羟基磷灰石的基础研究进展[J].生物骨科材料与临床研究,2017,14(3):62-66,69,6.基金项目
2013年云南省应用基础研究计划重点项目(2013FA057) （2013FA057）
2015年云南省科技厅-昆明医科大学应用基础研究联合资金项目(2015FB094) （2015FB094）
