实用医学杂志2017,Vol.33Issue(9):1445-1448,4.DOI:10.3969/j.issn.1006-5725.2017.09.021
嗜酸性粒细胞在尿源性脓毒血症中的临床意义
The Clinical Significance of Eosinophil in Urosepsis
摘要
Abstract
Objective To discuss The Clinical Significance of Eosinophil (EOS) in urosepsis. Methods A total of 99 patients of urosepsis in Department of Urology,Guangdong Provincial TCM Hospital from Mar. 2013 to Jul. 2016 were selected as research objects by retrospective analysis. The patients were classified into groupEOS= 0 andgroup EOS > 0,group PCT(procalcitonin)≥ 2 ng/mL andgroup PCT < 2 ng/mL,the differences of PCT concentration and percentage of EOS in two groups were analyzed comparatively. 99 patients of urosepsiswere also compared the difference of the percentage of EOS with another group including 100 patients of urinary tract infection (UTI) without Sepsis. Results The percentage of EOS was significantly decreased in 86.9%(86/99)of patients of urosepsis. The paired student t test show the percentage of EOS in two days after treatment,four days after treatment, before hospital discharge were higher than that before the treatment, the difference wassignificant (P < 0.05). The Independent-Sample Test show that the PCTconcentration in EOS = 0 group were higher than EOS > 0 group,the percentage of EOS in PCT≥2 ng/mL groupwere lower than PCT<2 ng/mL group,difference were significant(P<0.05). And The Independent-Sample Testalso showed that the percentage of EOS of the Urosepsis group was definitely lower than the UTI group without Sepsis. Difference was statistically significant. Concusions The percentage of EOS could be applied to assess the severity of urosepsis, monitor the disease progression and evaluate the infection control. The cost was lower than PCT in therapeuticprocess ofurosepsis.关键词
尿源性脓毒血症/嗜酸性粒细胞/降钙素原Key words
Urosepsis/Eosinophil/Procalcitonin引用本文复制引用
何君伟,曹家栋,王树声,翁湘涛,古炽明,李源,甘澍..嗜酸性粒细胞在尿源性脓毒血症中的临床意义[J].实用医学杂志,2017,33(9):1445-1448,4.基金项目
广东省中医院朝阳人才专项基金资助 ()