实用肿瘤杂志2017，Vol.32Issue(3)：244-248,5.
肠源性胃肠道间质瘤71例临床分析
Clinical analysis of 71 intestinal origin GIST cases
王战伟 1韩少良 2王晓红 1丁耘峰 1平金良3
作者信息
- 1. 湖州市中心医院普外科,浙江湖州313000
- 2. 温州医科大学附属第一医院胃肠外科,浙江温州325000
- 3. 湖州市中心医院病理科,浙江湖州313000
- 折叠
摘要
Abstract
Objective To investigate the clinicopathological features of gastrointestinal stromal tumors (GIST) and its prognostic factors.Methods The clinicopathological features and follow-up materials of 71 cases of surgically-treated GIST were analyzed retrospectively.Prognosis related risk factors were evaluated by univariate analysis.Results Among the 71 intestinal origin GIST patients,51 cases had their primary tumors located in small intestines,15 cases in colorectum,and 5 cases in esenterium.The major clinical manifestation was gastrointestinal bleeding (45.1％,32 cases),followed by abdominal discomfort and abdominal mass (22.5％,16 cases;16.9％,12 cases).One case was evaluated with very low risk of recurrence,16 cases with low risk,and 54 cases with high-risk.Univariate analysis showed that the maximum tumor diameter,mitotic phase and recurrence risk were all risk factors of disease prognosis (P ＜ 0.05).Moreover,in patients with high risk of recurrence,patients who took targeted drugs after the surgery have significantly better prognosis than those who did not (P ＜ 0.05).Conclusion Complete tumor resection combined with targeted therapy is the best treatment of intestinal GIST.The maximum tumor diameter,mitotic phase and recurence risk are independent prognostic factors of intestinal origin GIST.关键词
胃肠道间质肿瘤/病理学/胃肠道间质肿瘤/药物疗法/间皮瘤/病理学/免疫组织化学/预后Key words
gastrointestinal stromal tumors/pathology/gastrointestinal stromal tumors/drug therapy/mesothelioma/pathology/immunohistochemistry/prognosis分类
医药卫生引用本文复制引用
王战伟,韩少良,王晓红,丁耘峰,平金良..肠源性胃肠道间质瘤71例临床分析[J].实用肿瘤杂志,2017,32(3):244-248,5.
