生殖医学杂志2017，Vol.26Issue(7)：679-684,6.DOI:10.3969/j.issn.1004-3845.2017.07.012
男性年龄与精子质量和精浆生化的关系
Relationship between ages and sperm quality and seminal plasma biochemical indexes
摘要
Abstract
Objective:To investigate the relationship between age and sperm quality and biochemical indexes of seminal plasma.Methods:The clinical data of 3 262 patients with sperm quality and seminal plasma biochemistry indicators (seminal plasma elastase & α-glycosidase) in Jiaxing Maternal & Child Health Hospital were analyzed retrospectively.The patients were divided into 5 groups according to the age:<25 year group,25-29 year group,30-34 years group,35-39 years group and≥40 years group.In addition,the patients were divided into oligoasthenospermia (n=301),oligozoospermia (n=193) and asthenospermia (n=1335) and normal sperm group (n=1433) according to sperm quality.The correlation between the age or sperm quality and seminal plasma elastase & α-glycosidase was analyzed.Results:The abnormal rate of seminal plasma α-glycosidase was 7.14%,and the infection rate confirmed by seminal plasma elastase level was 29.25% in 3 262 patients.The abnormal rate of α-glycosidase was similar among the different age groups (P>0.05).The infection rate was significantly increased with age (P<0.05).The abnormal rate of α-glycosidase was significantly different among the different sperm quality groups (P<0.05).The abnormal rate of α-glycosidase in oligoasthenospermia or oligozoospermia was significantly higher than that of asthenospermia or normal sperm group (P<0.05),while the infection rate was similar (P>0.05).The abnormal rate of α-glycosidase was similar in different sperm quality group with the increase of age (P>0.05),while the abnormal rate of seminal plasma elastase was significantly increased with age (P<0.05),which also was significant different in the patients with oligoasthenospermia or oligozoospermia among the different age group (all P<0.05).The tendency of the seminal plasma elastase levels was increased with age in different sperm quality groups.Compared with<25 years old group,the seminal plasma elastase levels of normal sperm group with 35-39 years old and≥40 years old was significantly increased (P<0.05).Conclusions:Reproductive tract infection in male clinic patients is universality.Oligoasthenospermia,oligozoospermia,and asthenospermia in patients with difficult to self-healing of reproductive tract infections may be related the patients' age and the severity and advancement of infertile patients' accessory sex gland lesions.关键词
年龄/精子质量/弹性硬蛋白酶/中性α-葡萄糖苷酶Key words
Age/Sperm Quality/Elastasey/α-glycosidase引用本文复制引用
毛金观,彭忠英,李琴..男性年龄与精子质量和精浆生化的关系[J].生殖医学杂志,2017,26(7):679-684,6.基金项目
嘉兴市科技计划(2015AY23035) （2015AY23035）
