现代妇产科进展2017,Vol.26Issue(6):437-439,3.DOI:10.13283/j.cnki.xdfckjz.2017.06.008
Ets-1在子宫内膜癌中的表达及意义
The expression and clinical significance of Ets-1 in endometrial carcinoma
摘要
Abstract
Objective:To investigate the expression of Ets-1 in endometrial carcinoma tissues,the relationship between Ets-1 and clinical stage,pathological grading and typing of endometrial carcinoma.Methods:The expression of Ets-1 was detected in endometrial carcinoma and normal endometrium using imunohistochemical sp method and fluorescence in situ hybridization.Results:The positive expression of Ets-1 protein in endometrial carcinoma rate was 88.8%,was higher than normal endometrial tissue.The expression of Ets-1 in endometrial carcinoma was correlated with clinicopathological stage,muscular layer infiltration and pathological grading (P<0.05).Conclusion:Ets-1 is closely related to clinical stage,pathological grading and metastasis of endometrial carcinoma.关键词
子宫内膜癌/Ets-1/免疫组织化学/荧光原位杂交技术Key words
Ets-1 protein/Ets-1 mRNA/Endometrial carcinoma/Immunohistoche-mistry/Fluorescent in situ hybridization method分类
医药卫生引用本文复制引用
郝长宏,田永会,刘正玲,许宗兰..Ets-1在子宫内膜癌中的表达及意义[J].现代妇产科进展,2017,26(6):437-439,3.基金项目
山东省卫生厅基金(No:2014WS0290) (No:2014WS0290)