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Ets-1在子宫内膜癌中的表达及意义

郝长宏 田永会 刘正玲 许宗兰

现代妇产科进展2017,Vol.26Issue(6):437-439,3.
现代妇产科进展2017,Vol.26Issue(6):437-439,3.DOI:10.13283/j.cnki.xdfckjz.2017.06.008

Ets-1在子宫内膜癌中的表达及意义

The expression and clinical significance of Ets-1 in endometrial carcinoma

郝长宏 1田永会 1刘正玲 1许宗兰1

作者信息

  • 1. 山东省临沂市中心医院妇科,临沂 276400
  • 折叠

摘要

Abstract

Objective:To investigate the expression of Ets-1 in endometrial carcinoma tissues,the relationship between Ets-1 and clinical stage,pathological grading and typing of endometrial carcinoma.Methods:The expression of Ets-1 was detected in endometrial carcinoma and normal endometrium using imunohistochemical sp method and fluorescence in situ hybridization.Results:The positive expression of Ets-1 protein in endometrial carcinoma rate was 88.8%,was higher than normal endometrial tissue.The expression of Ets-1 in endometrial carcinoma was correlated with clinicopathological stage,muscular layer infiltration and pathological grading (P<0.05).Conclusion:Ets-1 is closely related to clinical stage,pathological grading and metastasis of endometrial carcinoma.

关键词

子宫内膜癌/Ets-1/免疫组织化学/荧光原位杂交技术

Key words

Ets-1 protein/Ets-1 mRNA/Endometrial carcinoma/Immunohistoche-mistry/Fluorescent in situ hybridization method

分类

医药卫生

引用本文复制引用

郝长宏,田永会,刘正玲,许宗兰..Ets-1在子宫内膜癌中的表达及意义[J].现代妇产科进展,2017,26(6):437-439,3.

基金项目

山东省卫生厅基金(No:2014WS0290) (No:2014WS0290)

现代妇产科进展

OA北大核心CSCDCSTPCD

1004-7379

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