中国组织工程研究2017，Vol.21Issue(18)：2920-2926,7.DOI:10.3969/j.issn.2095-4344.2017.18.021
可吸收防粘连膜的应用研究与未来展望
Research progress of absorbable anti-adhesion membranes
摘要
Abstract
BACKGROUND:Postoperative tissue adhesions can cause serious complications, resulting in the loss of body function, which deeply affects the patient's quality of life, and brings great threat to the life and health. Therefore, it is necessary to prevent postoperative tissue adhesion.OBJECTIVE:To summarize the achievement of absorbable anti-adhesion membrane in recent years, and to gain further insight into its advantages and disadvantages.METHODS: PubMed and CNKI were searched for relevant articles about anti-adhesion materials or products published from 2005 to 2016. The key words were "absorbable membrane, absorbability, anti-stiction, anti-adhesion, electrospinning, electrospun, nano-fiber, anti adhesion membrane/film, biodegradability" in Chinese and English, respectively. In accordance with the inclusion and exclusion criteria, 42 articles were reviewed.RESULTS AND CONCLUSION: Anti-adhesion membranes can effectively prevent postoperative adhesions, accelerate wound healing, and improve patients' quality of life. Bio-films, prepared using the film casting method, have the shortcomings of brittleness and poor toughness, which limit its clinical application. However, the anti-adhesion membrane made by electrostatic spinning technology has the advantages of high plasticity and good adhesiveness. It not only has the function of preventing adhesion, but also has a good biocompatibility during the tissue healing process. More fortunately, it can be degraded or absorbed in the postoperative period, showing its potential advantages. Nano-fiber products prepared by electro-spinning technology possess excellent characteristics, such as specific surface-area, high porosity, strong adsorption, fine fibrousness, excelent mechanical properties and so on, which have attracted much attention in the biomedical field. Such products have been also widely used in wound repair, tissue engineering and absorbable anti-adhesion membranes.关键词
生物材料/纳米材料/防粘连膜/可吸收性/防粘连/静电纺丝/纳米纤维/生物可降解性Key words
Tissue Adhesions/Biofilms/Biocompatible Materials/Tissue Engineering分类
医药卫生引用本文复制引用
陈灶妹,李茹冰..可吸收防粘连膜的应用研究与未来展望[J].中国组织工程研究,2017,21(18):2920-2926,7.基金项目
广东省产学研专项(2012B091100170).广州市科技计划项目(201509010012) the Production and Research Projects of Guangdong Province, No. 2012B091100170 （2012B091100170）
the Science and Technology Program of Guangzhou, No. 201509010012 （）
