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中国109例视神经脊髓炎谱系疾病的临床特点分析

丁秋爱 江娇美 游志鹏

眼科新进展2017,Vol.37Issue(6):548-550,3.
眼科新进展2017,Vol.37Issue(6):548-550,3.DOI:10.13389/j.cnki.rao.2017.0138

中国109例视神经脊髓炎谱系疾病的临床特点分析

Clinical features of neuromyelitisoptica spectrum disorders in 109 Chinese patients

丁秋爱 1江娇美 2游志鹏1

作者信息

  • 1. 330006江西省南昌市,南昌大学第二附属医院眼科
  • 2. 330006 江西省南昌市,南昌大学第二附属医院神经内科
  • 折叠

摘要

Abstract

Objective To investigate the clinical features of patients with neuromyelitisoptica spectrum disorders (NMOSD) in China.Methods Cases reports of NMOSD from 1989 to 2016 were retrieved from the database of Weipu data basis,and the clinical features of cases reported were analyzed.Results Eighty-seven studies were enrolled.Totally 109 patients were included.The ratio of male to female was 1 ∶ 4 and the mean onset age was (38.44 ± 17.08) years (range 5-76 years).The predisposing factors was catching a cold(12.80%).There were 66.05% patients with optic neuritis symptoms as initial symptoms,23.85% with spinal cord inflammation as the first symptom.Spinal magnetic resonance showed that 80.73% of the lesions involved thoracic spinal cord,and the cervical spinal cord occupied by 49.54%,while the lumbar spine accounted for about 10.09%.12.84% involved the final area.Conclusion In China,NMSOD is common in young adults,and more common in women.The onset age between the male and female has no significant difference.The first symptom of optic neuritis is more common,and the spinal cord lesion in thoracic cord is popular.

关键词

视神经脊髓炎谱系疾病/视神经炎/临床特点

Key words

neuromyelitisoptica spectrum disorders/optic neuritis/clinical feature

分类

医药卫生

引用本文复制引用

丁秋爱,江娇美,游志鹏..中国109例视神经脊髓炎谱系疾病的临床特点分析[J].眼科新进展,2017,37(6):548-550,3.

基金项目

国家自然科学基金资助(编号:81460088) (编号:81460088)

江西省高等学校科技落地计划项目(编号:KJLD14017) (编号:KJLD14017)

南昌大学研究生创新专项资金项目(编号:cx2016335) (编号:cx2016335)

National Natural Science Foundation of China (No:81460088) (No:81460088)

Higher School Science and Technology Floor Program of Jiangxi Province (No:KJLD14017) (No:KJLD14017)

Graduate Innovation and Special Project of Nanchang University (No:cx2016335) (No:cx2016335)

眼科新进展

OA北大核心CSTPCD

1003-5141

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