医药导报2017,Vol.36Issue(7):794-797,4.DOI:10.3870/j.issn.1004-0781.2017.07.018
对照提取物在银杏叶制剂特征图谱中的应用
Applications of Reference Eextract in Determining the Characteristic Spectrum of Ginkgo Leaf Preparations
摘要
Abstract
Objective To establish the characteristic spectrum of ginkgo leaf tablets,ginkgo leaf capsules,and ginkgo leaf dropping pills.Methods HPLC-ELSD analysis was performed on an Agilent Poroshell 120 EC-C18 column(150 mm×4.6 mm,2.7 μm)with the methanol-0.1% formic acid as mobile phase at the gradient elution mode,flow rate was 0.8 mL·min-1.Results Referring to the reference extract,a total of 12 peaks were established in the characteristic spectrum and selected as the characteristic common peaks.Conclusion The established method was simple and sensitive with good reproducibility,so it could be used to control the quality of ginkgo leaf preparations.关键词
银杏叶片/银杏叶胶囊/银杏叶滴丸/对照提取物/特征图谱Key words
Ginkgo leaf tablets/Ginkgo leaf capsules/Ginkgo leaf dropping pills/Reference extract/Characteristic spectrum分类
医药卫生引用本文复制引用
黄琴伟,赵维良,严爱娟,张文婷..对照提取物在银杏叶制剂特征图谱中的应用[J].医药导报,2017,36(7):794-797,4.基金项目
浙江省食品药品监管系统科技计划项目(2014005) (2014005)