中国临床心理学杂志2017，Vol.25Issue(3)：588-590,3.DOI:10.16128/j.cnki.1005-3611.2017.03.043
重复经颅磁刺激辅助治疗老年抑郁症的疗效观察
Clinical Efficacy of Repetitive Transcranial Magnetic Stimulation in Treatment of Late Life Depression
摘要
Abstract
Objective:To explore the clinical efficacy and safety of Repetitive transcranial magnetic stimulation(rTMS) in the treatment of late life depression.Methods:60 inpatients with late life depression in Tianjin Anding Hospital were enrolled in the study,who were randomized into control group and observation group.Control group received drug therapy (oral sertraline) and psychological intervention,while observation group received rTMS as the adjuvant treatment on the basis of the original treatment.The efficacy and adverse reactions were compared between the two groups before treatment and after 2 and 4 weeks.The Hamilton Depression Rating Scale(HAMD-24) and self rating Depression Scale(SDS) were used to assess the clinical efficacy.Results:At the baseline and 4th week,there was no significant difference in the HAMD and SDS scores between the two groups.At the 2nd week,there were significant differences of HAMD and SDS scores between the two group(P＜0.05).Compared with the baseline,SDS score,but not HAMD score,showed significant differences at the 2nd week in control group(P＞0.05);In observation group,the HAMD and SDS score at both 2nd and 4th week significantly decreased comparing to the baseline(P＜0.05).Adverse events showed no significant differences between two groups.Conclusion:Repetitive transcranial magnetic stimulation as adjuvant treatment of geriatric depression showed better,faster and safer therapeutic effects,as well as less adverse reactions on the geriatric depression.关键词
重复经颅磁刺激/老年抑郁症/临床疗效Key words
Repetitive transcranial magnetic stimulation/Late life depression/Clinical efficacy分类
医药卫生引用本文复制引用
顾培,仇玉莹,李晓征..重复经颅磁刺激辅助治疗老年抑郁症的疗效观察[J].中国临床心理学杂志,2017,25(3):588-590,3.基金项目
天津市卫生局科技基金,重点攻关项目(编号:12KG111) （编号:12KG111）
