中国临床医学2017，Vol.24Issue(3)：359-362,4.DOI:10.12025/j.issn.1008-6358.2017.20170432
国产新型电生理刺激反馈仪DS21在无创筛查糖尿病中的初步应用
Preliminary application of new electrophysiological stimulation feedback instrument DS21 in non-invasive screening diabetes
摘要
Abstract
Objective:To preliminarily assess the stability, effectiveness, and safety of the electrophysiological stimulation feedback instrument DS21 for non-invasive screening diabetes.Methods:Totally 46 cases were selected and divided into health control group (NC,n=17),impaired glucose regulation group(IGR, n=15), and diabetes group (DM, n=14) based on OGTT and diabetic history.All cases signed informed consent, were performed routine check-up and biochemical examination, and collected history, and underwent three times tests by electrophysiological stimulation feedback instrument.Three conductance values of this instrument were recorded for each case, the deviation of average values were calculated, to evaluate its stability and effectiveness, and the adverse reactions were observed.Results:The maximum of the mean conductance value deviation was 4.4, the minimum value was 0.2 in the 46 subjects, which were all less than 5.0, The conductance values were 77.9±5.2,70.4±5.7, and 54.7±11.4 in NC, IGR, and DM group, respectively.The trend of conductance value was NC >IGR > DM group.The difference of conductance values among groups was statistically significant (P<0.01).After adjusting for gender,age, and body mass index (BMI), the difference of conductance values among groups was still statistically significant (P<0.01).There was no adverse event in the test in 46 cases.Conclusions:Electrophysiological stimulation feedback instrument DS21 is stable, reliable.The conductance values are different in subject with different glucose metabolism.关键词
电生理刺激反馈仪/糖尿病/无创诊断Key words
electrophysiological stimulation feedback instrument/diabetes/noninvasive diagnosis分类
医药卫生引用本文复制引用
卞华,朱小鹏,颜红梅,常薪霞,夏明锋,高鑫..国产新型电生理刺激反馈仪DS21在无创筛查糖尿病中的初步应用[J].中国临床医学,2017,24(3):359-362,4.基金项目
国家自然科学基金(81471073),上海市卫生和计划生育委员会课题(2013ZYJB0802),上海市科委项目(13441900303),复旦大学附属中山医院优秀骨干计划(2015ZSYXGG15).Supported by National Natural Science Foundation of China(81471073) , Shanghai Municipal Commission of Health and Family Planning (2013ZYJB0802), Research Project of Science and Technology Commission of Shanghai Municipality (13441900303), and Excellent Member Program of Zhongshan Hospital Fudan University (2015ZSYXGG15). （81471073）
