中国临床医学2017，Vol.24Issue(3)：409-411,3.DOI:10.12025/j.issn.1008-6358.2017.20160783
康复新联合碱性成纤维细胞生长因子治疗慢性创面的临床疗效
The clinical efficacy of Kangfuxin combined with basic fibroblast growth factor in the treatment of chronic wound
许涛 1李卫 2吴晓峰 1黎明 1张初苗1
作者信息
- 1. 复旦大学附属金山医院烧伤整形科,上海 201508
- 2. 复旦大学附属金山医院体检科,上海 201508
- 折叠
摘要
Abstract
Objective:To evaluate the clinical efficacy of Kangfuxin combined with basic fibroblast growth factor in the treatment of chronic wound.Methods:A total of 60 patients with chronic wound were randomly divided into 3 groups with 20 patients in each group: Kangfuxin group, basic fibroblast growth factor group, and combined group.The wound healing rate and clinical efficacy in each group was evaluate and compared 3 weeks after treatment.The wound exudates in each group were continuously collected during the period of treatment wound exudate, and the IL-2 levels in wound exudates were measured by ELISA in each group.Results:The wound healing duration was significantly shorter in combined group than that in either Kangfuxin group or basic fibroblast growth factor group.The clinical efficacy in combined group was higher than that in either Kangfuxin group or basic fibroblast growth factor group (P<0.05).Additionally, the IL-2 level in combined group was significantly higher than that in either Kangfuxin group or basic fibroblast growth factor group 3 days after the treatment (P<0.05).Conclusions:The combined treatment of Kangfuxin and basic fibroblast growth factor is effective in improving the healing efficacy of chronic wound.关键词
康复新/碱性成纤维细胞生长因子/慢性创面/临床疗效Key words
Kangfuxin/basic fibroblast growth factor/chronic wound/clinical efficacy分类
医药卫生引用本文复制引用
许涛,李卫,吴晓峰,黎明,张初苗..康复新联合碱性成纤维细胞生长因子治疗慢性创面的临床疗效[J].中国临床医学,2017,24(3):409-411,3.
