中国临床医学2017，Vol.24Issue(3)：427-432,6.DOI:10.12025/j.issn.1008-6358.2017.20160765
绝经后妇女血维生素D水平与冠心病的相关性
Correlation between serum vitamin D level and coronary heart disease in postmenopausal women
摘要
Abstract
Objective:To analyze the relationship between serum level of 25-hydroxy vitamin D [25-(OH)D] and the prevalence of coronary heart disease (CHD) in postmenopausal women.Methods:A cross-sectional study was carried out in the physical examination center of Nanping First Hospital affiliated to Fujian Medical University with taking the physical examination crowd as the research objects.The level of 25-(OH)D in the peripheral blood of 440 postmenopausal women were detected by electrochemi-luminescence method, and the relationship between it and the prevalence of CHD and the risk factors were analyzed.Results:The serum 25-(OH)D level in 440 postmenopausal women was (23.3±8.8) ng/mL, and the deficiency rate was 69.1%, the insufficiency rate was 18.6%, and the normal rate was only about 12.3%.The prevalence of CHD in 25-(OH)D deficiency, insufficiency and normal postmenopausal women were 51.3%, 41.5%, and 20.4%, respectively.The difference was statistically significant (P<0.05).The level of 25-(OH)D in serum of postmenopausal women with different levels of high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and body mass index were different, and the differences were statistically significant (P<0.05).Conclusions:Serum 25-(OH)D level is significantly lower in postmenopausal women, and the degree of deficiency correlates with the prevalence of CHD.关键词
冠心病/25-羟维生素D/绝经Key words
coronary heart disease/25-hydroxy vitamin D/menopause分类
医药卫生引用本文复制引用
蒋凌,沈雪彬,叶桂云,陈昇,黄琦磊..绝经后妇女血维生素D水平与冠心病的相关性[J].中国临床医学,2017,24(3):427-432,6.基金项目
南平市级课题(N2014D012).Supported by Nanping City Subject (N2014D012). （N2014D012）
