中国临床医学2017，Vol.24Issue(3)：461-465,5.DOI:10.12025/j.issn.1008-6358.2017.20161017
生长分化因子11在衰老中的研究进展
Advances on aging of growth differentiation factor 11
摘要
Abstract
Growth differentiation factor 11(GDF11), a member of the transforming growth factor β(TGF-β)family, is widely expressed in many tissues.GDF11 regulates multiple developmental processes by reversing cell cycle arrest and reverses the aging process of many tissues including heart, skeletal muscle, brain, bone and blood vessels.In this article, we review the role of GDF11 in aging considering the TGF-β family signaling pathway and the mechanism of GDF11 in growth and development.关键词
生长分化因子11/衰老/转化生长因子βKey words
GDF11/aging/transforming growth factor-β分类
医药卫生引用本文复制引用
赵素洁,陆怡,吴晓琰..生长分化因子11在衰老中的研究进展[J].中国临床医学,2017,24(3):461-465,5.基金项目
上海市科学技术委员会重点项目科技创新行动(10431904000).Supported by the Key Program of Science and Technology Commission of Shanghai (10431904000). （10431904000）
