中国全科医学2017，Vol.20Issue(19)：2358-2362,5.DOI:10.3969/j.issn.1007-9572.2017.19.012
血小板/淋巴细胞比值对2型糖尿病患者发生糖尿病视网膜病变的诊断价值研究
Value of Platelet-to-lymphocyte Ratio in the Diagnosis of Diabetic Retinopathy in Type 2 Diabetes
摘要
Abstract
Objective To evaluate the value of platelet-to-lymphocyte ratio(PLR) in the diagnosis of diabetic retinopathy(DR) in type 2 diabetes.Methods The participants were 401 cases diagnosed with type 2 diabetes in Endocrine Department,Guilin People's Hospital from June 2012 to November 2014,including 200 complicated with DR(DR group),and 201 without(NDR group).Levels of biochemical markers venous blood sampled in early morning fasting state were measured and PLR was calculated.The value of PLR in the diagnosis of DR was assessed by the receiver operating characteristic(ROC) curve.Results The value of PLR in two groups was(113.7±56.0).The area under the ROC curve(AUC) of PLR for the diagnosis of DR in type 2 diabetes was 0.70 〔95%CI(0.65,0.75)〕,the optimal cut-off value was 103.9,with a sensitivity of 63.5% and a specificity of 69.2%.DR group and NDR group differed significantly in gender,age,course of diabetes,PLR value,levels of fasting blood glucose(FBG),glycosylated hemoglobin(HbA1c),high-density lipoprotein(HDL),and urine microalbuminuria(UMA)(P<0.05).Conclusion PLR plays a positive role in the diagnosis of DR in type 2 diabetes.Therefore,it may be recommended as a follow-up item for diabetes.关键词
糖尿病视网膜病变/血小板/淋巴细胞比值/诊断Key words
Diabetic retinopathy/Platelet-to-lymphocyte ratio/Diagnosis分类
医药卫生引用本文复制引用
张雪琳,刘霞,黎冬梅,伍雪云,丁毅,梁瑞向,黄芳..血小板/淋巴细胞比值对2型糖尿病患者发生糖尿病视网膜病变的诊断价值研究[J].中国全科医学,2017,20(19):2358-2362,5.基金项目
广西壮族自治区卫计委自筹经费课题(Z2014279) （Z2014279）
