中国全科医学2017，Vol.20Issue(20)：2451-2454,4.DOI:10.3969/j.issn.1007-9572.2017.20.005
肺尘埃沉着病合并高血压患者血管紧张素转化酶水平研究
Level of Angiotensin Converting Enzyme in Patients with Pneumoconiosis Complicated with Hypertension
摘要
Abstract
Objective To investigate the difference of serum angiotensin converting enzyme(ACE) level between patients with pneumoconiosis whether complicated with hypertension.Methods A total of 300 cases of pneumoconiosis patients admitted to the Guangdong Prevention and Treatment Center for Occupational Diseases were selected as study subjects from 2008 to 2015.The subjects were divided into pneumoconiosis combined with hypertension group(37 cases) and pneumoconiosis group(263 cases) according to whether hypertension was combined.The fasting venous blood of the patients was collected and the level of ACE was measured.Results The level of ACE in patients with pneumoconiosis was(124.75±75.45) U/L,which was higher than the upper limit of reference range (100.00 U/L),and the difference was statistically significant(t=5.635,P<0.05).Among them,ACE increased in 138 cases(46.0%).The age of pneumoconiosis combined with hypertension group was higher than that of pneumoconiosis group(P<0.05).The ACE levels between the two groups were compared,and there was no statistically significant difference(P>0.05).Linear regression analysis showed that there was no correlation between ACE level and gender,age,heart rate,systolic blood pressure,diastolic blood pressure,stage of pneumoconiosis and fasting blood glucose in patients with pneumoconiosis(P>0.05).Conclusion The level of ACE in pneumoconiosis patients is generally high,and there is no difference in ACE levels between the pneumoconiosis patients with or without hypertension.关键词
肺尘埃沉着病/高血压/血管紧张素转化酶Key words
Pneumoconiosis/Hypertension/Angiotensin converting enzyme分类
医药卫生引用本文复制引用
吴小苑,黄家文,樊春月..肺尘埃沉着病合并高血压患者血管紧张素转化酶水平研究[J].中国全科医学,2017,20(20):2451-2454,4.基金项目
国家临床重点专科建设项目 （）
