中国实验动物学报2017，Vol.25Issue(3)：340-344,5.DOI:10.3969/j.issn.1005-4847.2017.03.020
啮齿类动物注意定势转移任务研究进展
Research progress of the attentional set-shifting task in rodents
摘要
Abstract
Attentional set-shifting tasks are used as a measure of human fronto-executive function.the cognitive processes involved in forming an attentional set,maintaining an attentional set and shifting an attentional set are vulnerable to dysfunction arising from a number of human neurological disorders (such as attentional deficit/hyperactivity disorder,depression,schizophrenia) and neurodegenerative diseases (such as Parkinson's,Huntington's,Alzheimer's diseases).Recently,researches on rodents mainly continue to illustrate normal rats which are caused by different operating different performance in the attentional set-shifting tasks.And also there are few studies committed to observe the adaptability of the rats in attentional set-shifting tasks as well as different performance between species of rodents in attentional set shifting tasks.In addition,these results have elucidated the roles of multiple neurotransmitters in the manifestation of cognitive processes.This review focuses on the methodology of the attentional set-shifting tasks and the role of the neurotransmitter in cognitive processes.关键词
注意定势转移任务/啮齿类动物/多巴胺/乙酰胆碱/5-羟色胺/去甲肾上腺素Key words
Attentional set shifting task(ASST)/Rodents/Dopamine/Acetylcholine/5-serotonin/Norepinephrine分类
生物科学引用本文复制引用
侯兰伟,孙宏伟,王钢,连波,姜能志,孙琳..啮齿类动物注意定势转移任务研究进展[J].中国实验动物学报,2017,25(3):340-344,5.基金项目
山东省优秀中青年科学家科研奖励基金计划项目(编号:BS2014YY043) （编号:BS2014YY043）
山东省自然科学基金项目(编号:ZR2014CL012) （编号:ZR2014CL012）
潍坊医学院科技创新研究基金项目(编号:K1301011) （编号:K1301011）
潍坊医学院教育教学改革与研究基金项目(编号:2015Y024). （编号:2015Y024）
