中国比较医学杂志2017,Vol.27Issue(6):86-91,6.DOI:10.3969.j.issn.1671-7856.2017.06.018
斑马鱼模型在常见骨疾病研究中的应用
Application of zebrafish models in the research on bone diseases
摘要
Abstract
Zebrafish (Danio rerio), as a new vertebrate model organism, has been widely used in human disease research in recent years, especially in the study of human bone diseases.The zebrafish models show some advantages, such as expression of disease-related genes and application in pharmacodynamic screening and evaluation, etc.It is also of great practical significance for the traditional medicine, which has a characteristic efficacy in the treatment of bone diseases.This paper reviews the research and application of zebrafish in research on bone diseases such as osteoporosis, fracture, osteoarthritis, and so on, aiming to provide some inspiration for the future clinically relevant research.关键词
斑马鱼/骨疾病/动物模型Key words
Zebrafish/Bone diseases/Animal models分类
医药卫生引用本文复制引用
王小琦,孙岩,张洋,赵宏斌,李文辉..斑马鱼模型在常见骨疾病研究中的应用[J].中国比较医学杂志,2017,27(6):86-91,6.基金项目
国家自然科学基金委-云南省人民政府联合基金项目(编号:U150220034). (编号:U150220034)