中国实用内科杂志2017，Vol.37Issue(6)：564-568,5.DOI:10.19538/j.nk2017060121
2型糖尿病患者同型半胱氨酸和血压相关性分析
The correlation between blood pressure and homocysteine in Chinese type Ⅱ diabetes
摘要
Abstract
Objective Purpose This cross-sectional study is to explore the relationship between homocysteine and hypertension prevalence in Chinese type Ⅱ diabetes patients.Methods 401 type Ⅱ diabetes patients who received health examination in Peking University First Hospital were included in this study.Homocysteine was measured by cyclic enzymatic method.Blood pressure,BMI,medical history were recorded and blood biochemistry was tested.Multi logistic regression was used to analyze.Results lμmol/L and 1 SD log increase of homocysteine level can respectively lead to 5％ and 1.78 fold increase in the risk of hypertension.Analysis among each tertile of homocysteine showed the highest tertile associated with 1.05 fold increase in the risk of hypertension compared to the lowest tertile,and p value for trend is less than 0.05.Conclusions In Chinese type Ⅱ diabetes patients,serum homocysteine is associated with homocysteine,and the increase of blood pressure can induce the increase of the risk of hypertension.关键词
同型半胱氨酸/高血压/糖尿病Key words
homocysteine/hypertension/diabetes分类
医药卫生引用本文复制引用
翁浩宇,杨宏云,易铁慈,范芳芳,刘志浩,郝清清,范玲,张岩,李建平..2型糖尿病患者同型半胱氨酸和血压相关性分析[J].中国实用内科杂志,2017,37(6):564-568,5.基金项目
国家科技重大专项项目(2012ZX09101105) （2012ZX09101105）
