中国实用外科杂志2017，Vol.37Issue(6)：637-640,4.DOI:10.19538/j.cjps.issn1005-2208.2017.06.11
局部进展期直肠癌新辅助放化疗后手术最佳间隔时间选择
Optimal timing of surgery following neoadjuvant chemoradiotherapy in locally advanced rectal cancer
曹键 1叶颖江 1王杉1
作者信息
- 1. 北京大学人民医院胃肠外科,北京100044
- 折叠
摘要
Abstract
The standard treatment for locally advanced rectal cancer (LARC) is curative surgical resection,combined with neoadjuvant chemoradiation therapy (nCRT) and additional adjuvant therapy if indicated.But the optimal interval between CRT and surgery is still unclear.Prolonging the interval to 12 weeks may lead to significantly higher rates of tumor downstaging and pathologic complete response (pCR).However,delayed surgery may increase the technical difficulty,and reduce the quality of surgery.Whether prolonged interval can improve long-term outcome is uncertain.Individualized treatment strategies should be based on the patient's condition.关键词
局部进展期直肠癌/新辅助放化疗/手术/最佳间隔时间Key words
locally advanced rectal cancer/neoadjuvant chemoradiotherapy/surgery/optimal time interval分类
医药卫生引用本文复制引用
曹键,叶颖江,王杉..局部进展期直肠癌新辅助放化疗后手术最佳间隔时间选择[J].中国实用外科杂志,2017,37(6):637-640,4.
