中国实用外科杂志2017，Vol.37Issue(6)：644-648,5.DOI:10.19538/j.cjps.issn1005-2208.2017.06.13
NCCN《软组织肉瘤临床实践指南(2017年第2版)》胃肠间质瘤内容介绍与更新解读
Updates and interpretations of the NCCN Clinical Practice Guidelines (2017 second version) on gastrointestinal stromal tumor
汪明 1曹晖1
作者信息
- 1. 上海交通大学医学院附属仁济医院胃肠外科,上海200127
- 折叠
摘要
Abstract
The diagnosis and treatment of gastrointestinal stromal tumor (GIST) is getting more and more standardized.In the last decade,due to the revelation of the molecular mechanism of its tumorigenesis,as well as the effectiveness of tyrosine kinase inhibitors,GIST has become well known as one of the most classical models of targeted therapy on solid tumor in the precision medicine era.The National Comprehensive Cancer Network (NCCN) issued the latest version of clinical practice guideline on GIST in Feb.2017.The updated guideline standardized the principle of imaging and updated the predictor of GIST biological behavior.Given the newly emerged evidence from clinical trials,in the discussion chapter,the updated guideline also highlighted the prognostic value of mutational characteristics and the role of laparoscopic surgery in the treatment of GIST.The paper provides interpretations of the updates,aiming to improve the clinical practice of GIST.关键词
胃肠间质瘤/美国国家综合癌症网络/指南Key words
gastrointestinal stromal tumor/National Comprehensive Cancer Network/guideline分类
医药卫生引用本文复制引用
汪明,曹晖..NCCN《软组织肉瘤临床实践指南(2017年第2版)》胃肠间质瘤内容介绍与更新解读[J].中国实用外科杂志,2017,37(6):644-648,5.
