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硒结合蛋白1抗肿瘤作用研究进展

曾谷清 谭杏 廖力

中国现代医学杂志2017,Vol.27Issue(10):62-65,4.
中国现代医学杂志2017,Vol.27Issue(10):62-65,4.DOI:10.3969/j.issn.1005-8982.2017.10.012

硒结合蛋白1抗肿瘤作用研究进展

Research progress on antitumor effect of selenium binding protein 1

曾谷清 1谭杏 1廖力1

作者信息

  • 1. 南华大学护理学院,湖南,衡阳421001
  • 折叠

摘要

Abstract

Selenium binding protein 1 (SBP1) is a member of selenoprotein family,has been shown to covalently bind selenium and participate in the transportation of proteins in Golgi body.Many studies showed that SBP1 is a novel tumor suppressor protein closely related to tumor cell proliferation,differentiation and apoptosis.The aim of this paper is to investigate the correlations between selenium binding protein 1 and tumor occurrence,development,differentiation,proliferation,apoptosis,metastasis,chemotherapy sensitivity and prognosis,so as to provide a scientific guidance for early diagnosis and individualized therapy of tumors,improve the prognosis of tumor patients.

关键词

硒结合蛋白1/抗肿瘤/细胞增殖/化疗敏感性/预后

Key words

selenium binding protein 1/antitumor/cell proliferation/chemotherapy sensitivity/prognosis

分类

医药卫生

引用本文复制引用

曾谷清,谭杏,廖力..硒结合蛋白1抗肿瘤作用研究进展[J].中国现代医学杂志,2017,27(10):62-65,4.

基金项目

国家自然科学基金(No:81470130 ()

81272959) ()

南华大学博士科研启动基金(No:2013XQD33) (No:2013XQD33)

南华大学研究生科研创新项目(No:2016XCX41) (No:2016XCX41)

中国现代医学杂志

OACSTPCD

1005-8982

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