中国现代医学杂志2017,Vol.27Issue(10):62-65,4.DOI:10.3969/j.issn.1005-8982.2017.10.012
硒结合蛋白1抗肿瘤作用研究进展
Research progress on antitumor effect of selenium binding protein 1
摘要
Abstract
Selenium binding protein 1 (SBP1) is a member of selenoprotein family,has been shown to covalently bind selenium and participate in the transportation of proteins in Golgi body.Many studies showed that SBP1 is a novel tumor suppressor protein closely related to tumor cell proliferation,differentiation and apoptosis.The aim of this paper is to investigate the correlations between selenium binding protein 1 and tumor occurrence,development,differentiation,proliferation,apoptosis,metastasis,chemotherapy sensitivity and prognosis,so as to provide a scientific guidance for early diagnosis and individualized therapy of tumors,improve the prognosis of tumor patients.关键词
硒结合蛋白1/抗肿瘤/细胞增殖/化疗敏感性/预后Key words
selenium binding protein 1/antitumor/cell proliferation/chemotherapy sensitivity/prognosis分类
医药卫生引用本文复制引用
曾谷清,谭杏,廖力..硒结合蛋白1抗肿瘤作用研究进展[J].中国现代医学杂志,2017,27(10):62-65,4.基金项目
国家自然科学基金(No:81470130 ()
81272959) ()
南华大学博士科研启动基金(No:2013XQD33) (No:2013XQD33)
南华大学研究生科研创新项目(No:2016XCX41) (No:2016XCX41)