摘要
Abstract
Objective To explore the correlation between lower genital infection and premature rupture of membranes (PROM).Methods Totally 200 pregnant women with PROM who had babies in our hospital between March 2014 and March 2016 were selected as study group,while 200 normal pregnant women during the same period were selected as control group.C-reactive protein (CRP),routine examination of leucorrhea,bacterial vaginosis (BV),cervical secretions for Chlamydia trachomatis (CT),Ureaplasma parvum (UP),Mycoplasma hominis (MH) and group B Streptococcus (GBS) were analyzed in both groups.Results CRP of the study group was significantly higher than that of the control group (t =3.221,P < 0.05).The incidences of BV,infections caused by UP,CT,MH,GBS,Candida albicans,Tdchomonas vaginalis,and mixed infections in the study group were significantly higher than those in the control group (x2 =5.498,49.520,4.810,12.210,9.421,4.815,4.592 and 41.813 respectively,P < 0.05).The total infection rate of the study group (60%) was higher than that of the control group (26%),which had statistically significant difference (x2 =47.16,P < 0.05).The incidences of premature birth,pneumonia of newborn,neonatal asphyxia,and pathological jaundice in the newborns of the study group were significantly higher than those of the control group (x2 =17.330,33.006,9.355 and 4.891 respectively,P < 0.05),except the infants of low-birth weight (P > 0.05).The correlative factors of PROM were UP,MH,GBS,CT and Candida albicans infections;among which UP was the significantly correlative factor in PROM pregnant women (P < 0.05).Conclusions There are close correlations between the premature rupture of membranes and lower reproductive tract infections.The causes of PROM are closely related to UP,MH,GBS,CT and Candida albicans infections;UP infection is the most important factor.It is necessary to screen the pathogens in pregestational and pregnant stages and take the corresponding prevention and treatment measures so as to lower the occurrence of PROM and reduce the adverse effects of PROM on pregnant women and perinatal infants.关键词
胎膜早破/感染/宫颈分泌物/细小脲原体Key words
premature rupture of membrane/infection/cervical secretion/Ureaplasma parvum分类
医药卫生