中国现代医学杂志2017，Vol.27Issue(10)：94-97,4.DOI:10.3969/j.issn.1005-8982.2017.10.019
HbA1c水平与脑出血合并糖尿病患者迟发性脑水肿的相关性研究
Correlation of HbA1c value with severity of delayed cerebral edema in patients with ICH complicated with diabetes
刘兴宇 1甄艳凤 2崔建忠 1高俊玲 3王凯杰 1洪军1
作者信息
- 1. 河北省唐山市工人医院神经外科二科,河北唐山063000
- 2. 河北省唐山市工人医院内分泌二科,河北唐山063000
- 3. 华北理工大学基础医学院组织胚胎学教研室,河北唐山063000
- 折叠
摘要
Abstract
Objective To explore the correlation between glycated hemoglobin A1c (HbA1c) value and the severity of delayed cerebral edema in patients with intracerebral hemorrhage (ICH) complicated with diabetes.Methods A total of 115 patients of ICH complicated with diabetes hospitalized in Tangshan Gongren Hospital were retrospectively analyzed and divided into three groups:group A (HbA1c ＜ 7.0％),group B (7.0％ ≤ HbA1c ≤9.0％),and group C (HbA1c ＞ 9.0％) according to HbA1c level.High-pressure liquid chromatography (HPLC) was adopted to detect HbA1c.Glasgow Coma Scale (GCS) and the US National Institutes of Health Stroke Scale (NIHSS)were used to assess patients’ condition.Then the influence of HbA1c on delayed cerebral edema in the ICH patients was analyzed.Results The incidence of delayed cerebral edema was significant different among the three groups (all P ＜ 0.05).Edema volume of the patients with delayed cerebral edema was correlated with HbA1c,GCS and NIHSS score (r =0.814,-0.780 and 0.696 respectively;all P =0.000).Furthermore,HbA1c level was still correlated with the edema volume in multiple linear regression analysis (β =0.741,t =5.280,P =0.000).Conclusions HbA1c level is correlated with the severity of delayed cerebral edema in patients with intracerebral hemorrhage complicated with diabetes.关键词
脑出血/糖尿病/迟发性脑水肿/发生率/糖化血红蛋白Key words
intracerebral hemorrhage/diabetes/delayed cerebral edema/incidence/glycated hemoglobin A1c分类
医药卫生引用本文复制引用
刘兴宇,甄艳凤,崔建忠,高俊玲,王凯杰,洪军..HbA1c水平与脑出血合并糖尿病患者迟发性脑水肿的相关性研究[J].中国现代医学杂志,2017,27(10):94-97,4.
