中国畜牧杂志2017,Vol.53Issue(6):4-10,7.DOI:10.19556/j.0258-7033.2017-06-004
睾丸发育与精子发生相关miRNAs的研究进展
Research Progress on miRNAs in Testis Development and Spermatogenesis
摘要
Abstract
miRNAs are a class of non-coding small RNA,which are widely existed in eukaryotes and involved in regulating different biological processes,miRNAs can degrade the target gene or inhibit the gene translation by targeting 3'UTR of mRNAs at the post transcriptional level to regulate the expression of gene.The cell specific regulation of miRNAs in spermatogenesis is important to regulate male reproduction.This article reviewed the biosynthesis,mechanism and especially the expressions of miRNAs in testis development and spermatogenesis,which provides a reference for further research on the role and molecular regulation mechanism of miRNAs in male reproduction.关键词
miRNAs/生物合成/表达调控/睾丸发育/精子发生Key words
miRNAs/Biosynthesis/Expression regulation/Testis development/Spermatogenesis分类
医药卫生引用本文复制引用
白曼,孙丽敏,项露颉,贾超,李佳蓉,姜怀志..睾丸发育与精子发生相关miRNAs的研究进展[J].中国畜牧杂志,2017,53(6):4-10,7.基金项目
吉林省科技发展计划项目(20160204018NY) (20160204018NY)