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睾丸发育与精子发生相关miRNAs的研究进展

白曼 孙丽敏 项露颉 贾超 李佳蓉 姜怀志

中国畜牧杂志2017,Vol.53Issue(6):4-10,7.
中国畜牧杂志2017,Vol.53Issue(6):4-10,7.DOI:10.19556/j.0258-7033.2017-06-004

睾丸发育与精子发生相关miRNAs的研究进展

Research Progress on miRNAs in Testis Development and Spermatogenesis

白曼 1孙丽敏 1项露颉 1贾超 1李佳蓉 1姜怀志1

作者信息

  • 1. 吉林农业大学动物科学技术学院,吉林长春 130118
  • 折叠

摘要

Abstract

miRNAs are a class of non-coding small RNA,which are widely existed in eukaryotes and involved in regulating different biological processes,miRNAs can degrade the target gene or inhibit the gene translation by targeting 3'UTR of mRNAs at the post transcriptional level to regulate the expression of gene.The cell specific regulation of miRNAs in spermatogenesis is important to regulate male reproduction.This article reviewed the biosynthesis,mechanism and especially the expressions of miRNAs in testis development and spermatogenesis,which provides a reference for further research on the role and molecular regulation mechanism of miRNAs in male reproduction.

关键词

miRNAs/生物合成/表达调控/睾丸发育/精子发生

Key words

miRNAs/Biosynthesis/Expression regulation/Testis development/Spermatogenesis

分类

医药卫生

引用本文复制引用

白曼,孙丽敏,项露颉,贾超,李佳蓉,姜怀志..睾丸发育与精子发生相关miRNAs的研究进展[J].中国畜牧杂志,2017,53(6):4-10,7.

基金项目

吉林省科技发展计划项目(20160204018NY) (20160204018NY)

中国畜牧杂志

OA北大核心CSTPCD

0258-7033

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