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百令胶囊治疗呼吸系统疾病有效性的系统评价

张亚同 刘泽辉 胡欣

中国药房2017,Vol.28Issue(18):2516-2519,4.
中国药房2017,Vol.28Issue(18):2516-2519,4.DOI:10.6039/j.issn.1001-0408.2017.18.20

百令胶囊治疗呼吸系统疾病有效性的系统评价

Systematic Evaluation of the Effectiveness of Corbrin Capsules for Respiratory System Disease

张亚同 1刘泽辉 1胡欣2

作者信息

  • 1. 北京医院国家老年医学中心,北京 100730
  • 2. 北京大学药学院药事管理与临床药学系,北京 100191
  • 折叠

摘要

Abstract

OBJECTIVE:To evaluate the effectiveness of Corbrin capsules for respiratory systemdisease systematically,in or-der to provide evidence-based reference for clinical use. METHODS:Retrieved from CJFD,China Dissertation Database,Wanfang database,VIP,Cochrane Library,Medline and PubMed,randomized controlled trials(RCTs)about conventional treatment plan(trial group)vs. single treatment plan(control group)in the treatment of respiratory system disease. The quality of included studies were evaluated after extracting data and modifying according to Jadad scale and Cochrane bias risk assessment scale. Meta-analysis was performed by using RevMan 5.2 statistical software. RESULTS:A total of 17 RCTs were included,involving 1801 patients. The re-sults of Meta-analysis showed that response rate [RD=0.15,95%CI(0.10,0.19),P<0.001],FEV1[MD=0.21,95%CI(0.14,0.28), P<0.001],FVC [MD=0.26,95%CI(0.05,0.47),P<0.001] and FEV1/FEV [MD=5.60,95%CI(3.42,7.78),P<0.001] of trial group were significantly higher than those of control group,with statistical significance. CONCLUSIONS:Corbrin capsules have good therapeutic efficacy for respiratory system disease and effectively improve lung related indicators.

关键词

百令胶囊/呼吸系统/有效性/系统评价/Meta分析

Key words

Corbrin capsules/Respiratory system disease/Effectiveness/Systematic evaluation/Meta-analysis

分类

医药卫生

引用本文复制引用

张亚同,刘泽辉,胡欣..百令胶囊治疗呼吸系统疾病有效性的系统评价[J].中国药房,2017,28(18):2516-2519,4.

基金项目

国家科技支撑计划课题(No.2012BAI0B00) (No.2012BAI0B00)

中国药房

OA北大核心CSTPCD

1001-0408

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