中国药房2017,Vol.28Issue(18):2516-2519,4.DOI:10.6039/j.issn.1001-0408.2017.18.20
百令胶囊治疗呼吸系统疾病有效性的系统评价
Systematic Evaluation of the Effectiveness of Corbrin Capsules for Respiratory System Disease
摘要
Abstract
OBJECTIVE:To evaluate the effectiveness of Corbrin capsules for respiratory systemdisease systematically,in or-der to provide evidence-based reference for clinical use. METHODS:Retrieved from CJFD,China Dissertation Database,Wanfang database,VIP,Cochrane Library,Medline and PubMed,randomized controlled trials(RCTs)about conventional treatment plan(trial group)vs. single treatment plan(control group)in the treatment of respiratory system disease. The quality of included studies were evaluated after extracting data and modifying according to Jadad scale and Cochrane bias risk assessment scale. Meta-analysis was performed by using RevMan 5.2 statistical software. RESULTS:A total of 17 RCTs were included,involving 1801 patients. The re-sults of Meta-analysis showed that response rate [RD=0.15,95%CI(0.10,0.19),P<0.001],FEV1[MD=0.21,95%CI(0.14,0.28), P<0.001],FVC [MD=0.26,95%CI(0.05,0.47),P<0.001] and FEV1/FEV [MD=5.60,95%CI(3.42,7.78),P<0.001] of trial group were significantly higher than those of control group,with statistical significance. CONCLUSIONS:Corbrin capsules have good therapeutic efficacy for respiratory system disease and effectively improve lung related indicators.关键词
百令胶囊/呼吸系统/有效性/系统评价/Meta分析Key words
Corbrin capsules/Respiratory system disease/Effectiveness/Systematic evaluation/Meta-analysis分类
医药卫生引用本文复制引用
张亚同,刘泽辉,胡欣..百令胶囊治疗呼吸系统疾病有效性的系统评价[J].中国药房,2017,28(18):2516-2519,4.基金项目
国家科技支撑计划课题(No.2012BAI0B00) (No.2012BAI0B00)