中国药业2017，Vol.26Issue(11)：4-8,5.DOI:10.3969/j.issn.1006-4931.2017.11.002
土大黄根提取物对实验性银屑病小鼠支配器官形态学的影响
Effect of Rumex L. Root Extract on Morphology of Dominant Organs in Mice with Experimental Psoriasis
摘要
Abstract
Objective To investigate the effects of Rumex L. root extract on the morphology of dominant organs in mice with experimen-tal psoriasis. Methods The experimental psoriasis model was established in BALB/c mice by applying Imiquimod ( IMQ ) cream, then to observe the effects of Rumex L. root extract ( 1, 2, 4 g/kg ) on mice′s dominating organs such as brain, heart, liver, organ index and morphology. Results Compared with the model group, the effects of 1, 2, 4 g/kg groups on the brain, heart, liver and organ index of mice had no statistically different ( P > 0. 05 ) , at the same time, there was no obvious abnormality in brain and heart morphology, but it could cause liver cell regeneration, acidophilic degeneration. Conclusion Rumex L. root extract can protect and repair the morphological damage of dominating organ of liver on experimental psoriasis mice by induced IMQ.关键词
土大黄根/实验性银屑病/支配器官/形态学Key words
Rumex L. root/experimental psoriasis/dominating organ/morphology分类
医药卫生引用本文复制引用
艾西木江·热甫卡提,麦合素提·卡迪尔,阿不都吉力力·阿布都艾尼,再妮皮古丽·巴拉提,热比姑丽·伊斯拉木..土大黄根提取物对实验性银屑病小鼠支配器官形态学的影响[J].中国药业,2017,26(11):4-8,5.基金项目
新疆维吾尔自治区卫生计生委青年科技人才专项科研项目[ 2015Y40 ]. （）
