摘要
Abstract
Objective To investigate the clinical efficacy of Ambroxol Hydrochloride Injection in the treatment of neonatal respiratory distress syndrome. Methods Totally 200 children patients with neonatal respiratory distress syndrome admitted to our hospital from September 2014 to January 2016 were selected and randomly divided into the observation group and the control group, 100 cases in each group. The control group was given mechanical ventilation, anti-infection and supportive treatment on the basis of conventional treatment, while the observation group was treated with Ambroxol Hydrochloride Injection patients on the basis of the control group. The PaO2, PA-aDO2, PaO2/FiO2, and the levels of plasma ET-1 in the two groups before treatment and after treatment on the 5th day were compared. Results After treatment, the PaO2, PA-aDO2, PaO2/FiO2, and the level of ET-1 in the two groups were significantly better than before treatment, and those in the observation group were significantly better than those in the control group ( P < 0. 05 ) . The heart rate, respiratory, oxygenation index and hospitalization time in the observation group were significantly better than those in the control group ( P < 0. 05 ) . Conclusion Ambroxol Hydrochloride Injection can effectively improve the oxygenation status in children with respiratory distress syndrome and decrease the level of plasma ET-1.关键词
盐酸氨溴索/呼吸窘迫综合征/新生儿/内皮素-1/临床疗效Key words
Ambroxol Hydrochloride Injection/respiratory distress syndrome/neonate/endothelin-1/clinical efficacy分类
医药卫生
