中国药业2017，Vol.26Issue(12)：38-40,3.DOI:10.3969/j.issn.1006-4931.2017.12.010
5α还原酶抑制剂联用α受体阻断剂对老年良性前列腺增生下尿路症状的效果及护理要点
Clinical Effect of 5α Reductase Inhibitors Combined with α Receptor Blockers in Treating Lower Urinary Tract Symptoms in Elderly Patients with Benign Prostatic Hyperplasia and Its Main Nursing Points
摘要
Abstract
Objective To investigate the clinical effect of 5α reductase inhibitors combined with α receptor blockers in treating lower urinary tract symptoms(LUT)in elderly patients with benign prostatic hyperplasia(BPH)and its main nursing points. Methods Totally 162 elderly patients with BPH in our hospital were selected and divided into the control group and the experimental group by the ran-dom number table method,81 cases in each group. The two groups were treated with 5α reductase inhibitors combined with α receptor blockers for 6 weeks. During the treatment,the control group was given routine nursing,and on the basis,the observation group were given detail nursing. International prostate symptom scores(IPSS)were used before and after treatment. The urine flow rate and residual urine volume in the two groups were recorded,the incidence of adverse events was statistically analyzed,and the main nursing points were summarized. Results The IPSS scores,maximum urine flow rate and residual urine volume of two groups decreased significantly after treatment,and those in the experimental group decreased significantly than those in the control group(P < 0. 05). The incidence rate of adverse reactions in the control group was 14. 08%,which was significantly higher than 3. 89% in the experimental group (P < 0. 05). Conclusion 5α reductase inhibitors combined with α receptor blockers is significantly effective in the treatment of LUT in elderly patients with BPH. In clinical practice,nursing measures should be taken according to patients′ dizziness,headache,mental quality and life style to reduce adverse reactions and improve the curative effect.关键词
5α还原酶抑制剂/α受体阻断剂/老年/良性前列腺增生/下尿路症状/护理Key words
5α reductase inhibitor/α receptor blocker/elderly/benign prostatic hyperplasia/lower urinary tract symptoms/nursing分类
医药卫生引用本文复制引用
刘竹芳,黄文柱,刘敏,周梅..5α还原酶抑制剂联用α受体阻断剂对老年良性前列腺增生下尿路症状的效果及护理要点[J].中国药业,2017,26(12):38-40,3.基金项目
广东省佛山市省级医学重点专科培育项目[ Fspy3-2015027 ]. （）
