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移植肾失功患者左心室结构与功能分析

陈丽莉 张萍 陈江华

浙江医学2017,Vol.39Issue(12):961-963,975,4.
浙江医学2017,Vol.39Issue(12):961-963,975,4.DOI:10.12056/j.issn.1006-2785.2017.39.12.2017-456

移植肾失功患者左心室结构与功能分析

Left ventricular structure and function in renal transplant patients after graft failure

陈丽莉 1张萍 2陈江华2

作者信息

  • 1. 310013杭州,浙江医院肾内科
  • 2. 浙江大学医学院附属第一医院肾脏病中心
  • 折叠

摘要

Abstract

Objective To investigate the left ventricular structure and function in renal transplant patients after graft failure.Methods Thirty nine renal graft failure patients undergoing maintenance hemodialysis (graft failure group) and 46 nontransplant patients with end-stage renal disease undergoing hemodialysis (primary hemodialysis group) were enrolled in the study.The Doppler echocardiography and laboratory examinations were performed before primary dialysis.The laboratory parameters,left ventricular structure and function indexes were compared between the two groups.Results There were no significant differences in Hb,serum albumin,TC,TG,parathyroid hormone between the two groups (P >0.05).The serum creatinine,serum iron,total iron binding capacity and transferrin saturation in renal graft failure group were lower,and the C reactive protein was higher than those in primary hemodialysis group (P<0.05).There were no significant differences between the two groups in left atrial diameter,left ventricular systolic and diastolic end diameter,left ventricular ejection fraction,and left ventricular short axis shortening rate (P >0.05).The ventricular septal end systolic thickness,ventricular septal end diastolic thickness,left ventricular posterior wall end systolic thickness,left ventricular posterior wall end diastolic thickness and left ventricular mass index in the renal graft failure group were higher than those in primary hemodialysis group (P<0.05).The incidence of left ventricular hypertrophy was higher in the renal graft failure group (P<0.05).There was no significant difference in the incidence of left ventricular systolic and diastolic dysfunction between the two groups(P >0.05).Conclusion The general state,cardiac structure and function in kidney-allograft-loss patients are poor,which may be associated with the use of immunosuppressive agents.

关键词

肾移植/移植肾失功/左心室结构/左心室功能

Key words

Renal transplant/Kidney allograft loss/Left ventricular structure/Left ventricular function

引用本文复制引用

陈丽莉,张萍,陈江华..移植肾失功患者左心室结构与功能分析[J].浙江医学,2017,39(12):961-963,975,4.

浙江医学

OACSTPCD

1006-2785

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