中国现代中药2017，Vol.19Issue(4)：496-499,508,5.DOI:10.13313/j.issn.1673-4890.2017.4.005
液质联用鉴定单面针中的化学成分
Identification of Chemical Ingredient in Zanthoxylum dissitum Hemsl.by LC-MS
摘要
Abstract
Objective:To rapidly identify alkaloids in Zanthoxylum dissitum Hemsl.using the LC-MS.Methods:The separation was performed on a XAqua C8column(150 mm ×2.1 mm,5 μm)with acetonitrile-0.1％ formic in water by gradient elution.The flow rate was 0.3 mL· min-1.Electrospray ionization-(ESI) source was applied and operated in positive ion mode.The structure of alkaloids was speculated by MS/MS fragmentation behaviors of standards and related references.Results:20 alkaloids were elucidated from the methanolic extracts of Z.dissitum.Conclusion:It is a rapid and reliable method to identify the alkaloids in Z.dissitum by LC-MS.The result would provide scientific evidence for development and utilization and study of pharmacodynamic material basis in this plants.关键词
单面针/生物碱Key words
Zanthoxylum dissitum Hemsl./alkaloids引用本文复制引用
宛玉祥,李家宇,秦优,周卿意骏,蔡萍,张水寒..液质联用鉴定单面针中的化学成分[J].中国现代中药,2017,19(4):496-499,508,5.基金项目
湖南省科技厅项目(2016JJ4055) （2016JJ4055）
