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杭白芷正丁醇溶性部位化学成分研究

韦玮 杨秀伟 周媛媛

中国现代中药2017,Vol.19Issue(5):630-634,5.
中国现代中药2017,Vol.19Issue(5):630-634,5.DOI:10.13313/j.issn.1673-4890.2017.5.007

杭白芷正丁醇溶性部位化学成分研究

Chemical Constituents from n-Butanol Soluble Parts of Roots of Angelica dahurica cvHangbaizhi

韦玮 1杨秀伟 1周媛媛2

作者信息

  • 1. 北京大学天然药物及仿生药物国家重点实验室,北京大学 药学院 天然药物学系,北京 100191
  • 2. 黑龙江中医药大学药学院,黑龙江 哈尔滨 150040
  • 折叠

摘要

Abstract

Objective:To study the chemical constituents of n-butanol soluble parts of 70% ethanol aqueous extract of the roots of Angelica dahurica cvHangbaizhiMethods:The compounds were separated and purified by repeated column chromatography on silica gel and HPLC,and their structures were elucidated by spectroscopic data analysesResults:Eleven compounds were obtained and identified as oxypeucedanin hydrate(1),heraclenol(2),(-)-marmesinin(3),(2'S,3'R)-3'-hydroxymarmesinin(4),sec-O-β-D-glucopyranosyl-byakangelicin(5),tert-O-β-D-glucopyranosyl-byakangelicin(6),(2'R,3'S)-3'-hydroxynodakenin(7),xanthotoxol-8-O-β-D-glucopyranoside(8),adenosine(9),byakangelicin(10),and pabulenol(11),respectivelyConclusion:The principal chemical constituents are free-coumarins and glucosides in the n-butanol soluble parts of 70%ethanol aqueous extract of the roots of Adahurica cvHangbaizhi.

关键词

杭白芷/伞形科/香豆素类/生物活性物质基础

Key words

Roots of Angelica dahurica cvHangbaizhi/Umbelliferae/coumarins/bioactive substance foundation

引用本文复制引用

韦玮,杨秀伟,周媛媛..杭白芷正丁醇溶性部位化学成分研究[J].中国现代中药,2017,19(5):630-634,5.

基金项目

国家自然科学基金项目(81473321). (81473321)

中国现代中药

OACSTPCD

1673-4890

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