中医药信息2017，Vol.34Issue(3)：17-20,4.
生川乌片炮制过程中5-HMF含量随炮制时间的变化规律研究
Changes of 5-hydroxymethylfurfuraldehyde Content in Radix Aconiti Tablets Processed at Different Time Points
摘要
Abstract
Objective:To find the changing regularity of 5-Hydroxymethylfurfuraldehyde (5-HMF) content in Radix Aconiti tablets processed at different time points.Methods:HPLC was used to determine the changes of 5-HMF content in different processed products of Radix Aconiti.Results:The content of 5-HMF of the raw product was 4.45 μg/g.The content of 5-HMF was increased within the first six hours of heating.At the same processing time,the content of steamed products was significantly higher than that of boiled products.Conclusion:An HPLC method for determining the content of 5-HMF has been established.The proposed method is stable and reliable.The changes of the content of 5-HMF of Radix Aconiti tablets are processed by steaming and boiling for two kinds,which were associated with the heating time.It provides a reference for the quality control of Radix Aconiti.关键词
生川乌片/炮制/HPLC/5-羟甲基糠醛Key words
Radix Aconiti tablets/Processing/HPLC/5-hydroxymethylfurfural分类
医药卫生引用本文复制引用
王蕾,张语凡,王鑫,彭诗涛,袁金凤,张先灵,陈炯,李飞..生川乌片炮制过程中5-HMF含量随炮制时间的变化规律研究[J].中医药信息,2017,34(3):17-20,4.基金项目
国家中医药行业科研专项资助项目(No.201107008) （No.201107008）
科技部科技基础性工作专项资助项目(No.2014FY111100-3) （No.2014FY111100-3）
